TEG-guided Resuscitation is Superior to Standardized MTP Resuscitation in Massively Transfused Penetrating Trauma Patients
In this study we hypothesized that TEG-directed resuscitation is equivalent to massive transfusion protocol resuscitation.
PHD2 Silencing Enhances the Survival and Paracrine Function of Transplanted Adipose-Derived Stem Cells in Infarcted Myocardium
We studied if and how Prolyl hydroxylase domain protein 2 silencing in human adipose-derived stem cells (ADSCs) enhances their cardioprotective effects after transplantation into infarcted hearts.
Processed Residual Pump Blood in Cardiac Surgery: The Processed Residual Blood in Cardiac Surgery Trial
This study seeks to establish if processing residual CPB volume with ultrafiltration reduces homologous blood transfusion and bleeding.
Diagnosis and Management of Primary Aldosteronism: An Updated Review
Utilizing a physician-centered approach, we intend to provide up-dated information on the etiology, diagnosis, and the management of Primary Aldosteronism.
Open Aortic Valve Replacement in a Patient with Glanzmann’s Thrombasthenia: A Multidisciplinary Strategy to Minimize Perioperative Bleeding
Patients with GT requiring cardiac surgical procedures are at high risk for perioperative bleeding complications. This case report illustrates the importance of multidisciplinary planning, TEG analysis, and the judicious use of recombinant factors to minimize operative bleeding risk.
Earlier Detection of Coagulopathy with Thromboelastometry During Pediatric Cardiac Surgery: A Prospective Observational Study
This study helps to determine whether thromboelastometry (TEM) analysis before weaning from cardiopulmonary bypass (CPB) and hemoconcentration is predictive of post-CPB results and whether analysis of clot firmness already after 10 min yields reliable results.
The Relationship Between Fibrinogen Levels After Cardiopulmonary Bypass and Large Volume Red Cell Transfusion in Cardiac Surgery: An Observational Study
The relationship between post-CPB fibrinogen levels and large volume red cell transfusion was explored in this study.
Evaluation of Coagulation Factors and Platelet Function from an Off-Line Modified Ultrafiltration Technique for Post-Cardiopulmonary Bypass Circuit Blood Recovery
This study evaluated the off-line MUFprocess of the Hemobag (HB, Global Blood Resources, Somers, CT, USA) to quantitate coagulation factor levels, platelet (PLT) count and function in one facility and cellular growth factor concentrations of the final product that were transfused to the patient in another facility
Zero Balance Ultrafiltration for the Correction of Acute Acidosis after a Period of Prolonged Deep Hypothermic Circulatory Arrest
Our case illustrates that Z-BUF offers a valuable option for the correction of severe electrolyte and acid-base disturbances in adults undergoingcardiac surgery.
The Effect of Normovolemic Modified Ultrafiltration on Inflammatory Mediators, Endotoxins, Terminal Complement Complexes and Clinical Outcome in High-Risk Cardiac Surgery Patients
The clinical benefit of normovolemic modified ultrafiltration (N-MUF) after cardiac surgery is still debated. As we have shown in a previous publication, there is a significant improvement in platelet function, so we were interested in whether ultrafiltration can reduce plasma levels of endotoxins, terminal complement complexes and cytokines after cardiopulmonary bypass (CPB) in adults with increased risk profiles.
Blood Transfusion and Infection after Cardiac Surgery
This study characterizes the relationship between transfusion and risk of major infection after cardiac surgery.
Novel Ultrafiltration Technique for Blood Conservation in Cardiac Operations
The performance characteristics and clinical outcome of a novel hemoconcentrator, the HemoSep (Brightwake, Nottingham, United Kingdom), for reusing salvaged blood postoperatively were evaluated.