Antifactor Xa Monitoring and Hematologic Complications of Pediatric Extracorporeal Membrane Oxygenation
Management of anticoagulation based on anti-Xa levels appears to be as effective as management based on ACT results.
Neurological Pupil index for Early Prognostication After Venoarterial Extracorporeal Membrane Oxygenation
Quantitative NPi alone had excellent ability to predict a poor outcome from day 1 after VA-ECMO insertion, with no false positives. Combining NPi and 12-h PREDICT-VA ECMO score increased the sensitivity of outcome prediction, while maintaining 100% specificity.
Thrombotic Risk in Central Venoarterial Extracorporeal Membrane Oxygenation Post Cardiac Surgery
Stasis is the predominant risk factor for intracardiac thrombosis. This occurs rapidly and the outcome is poor. As a result, we suggest early left ventricular decompression. Conventional management of post-bypass coagulopathy seems safe if the aortic valve is opening.
Air in Extracorporeal Membrane Oxygenation: Can Never be Overemphasized
Air in the extracorporeal membrane oxygenation circuit should never be overemphasized, especially during special procedures.
Childhood Extracorporeal Membrane Oxygenation Survivors: Parents Highlight Need for Structured Follow-Up and Support After Hospital Discharge
A proportion of children who have undergone extracorporeal membrane oxygenation treatment have needs that are not being met, with variable access to service provision.
ECMO Use in COVID-19: Lessons from Past Respiratory Virus Outbreaks—a Narrative Review
Here, we review the experience with the use of ECMO in the past respiratory virus outbreaks and discuss potential role for ECMO in COVID-19.
Safety and Efficacy of a Novel Pneumatically Driven Extracorporeal Membrane Oxygenation Device
The pneumatically driven ECMO device provided excellent safety and physiologic efficacy in a 7-day sheep experiment without visible clotting, hemolysis, or sustained reductions in fibrinogen or platelets.
Validation of the ‘Paediatric Extracorporeal Membrane Oxygenation Prediction’ Model in a UK Extracorporeal Membrane Oxygenation Centre
This small single-centre study with a small number of events was unable to validate the paediatric extracorporeal membrane oxygenation prediction-model of risk-adjustment. Although this remains the most promising of all the available models, further validation in larger data sets and/or refinement may be required before widespread use.
Fixed and Dilated Pupils, Not a Contraindication for Extracorporeal Support: a Case Series
The patients described demonstrate that fixed and dilated pupils are not a contraindication for extracorporeal support in select patients.
Association Between Low pH and Unfavorable Neurological Outcome among Out-of-hospital Cardiac Arrest Patients Treated by Extracorporeal CPR: a Prospective Observational Cohort Study in Japan
This multi-institutional observational study showed that low pH value (< 7.03) before the implementation of ECPR was associated with 1 month unfavorable neurological outcome among OHCA patients treated with ECPR. It may be helpful to consider the candidate for ECPR.
Cannula and Circuit Management in Peripheral Extracorporeal Membrane Oxygenation: An International Survey of 45 Countries
An evidence-based guideline would be beneficial to improve ECMO line management according to 78% of respondents. Evidence gaps were identified for antiseptic agents, dressing products and regimens, securement methods, and needleless valves. Future research addressing these areas may provide opportunities for consensus guideline development and practice improvement.
Extracorporeal Membrane Oxygenation Support for Pediatric Burn Patients: Is It Worth the Risk?
Extracorporeal membrane oxygenation could be considered as an additional level of support for the pediatric burn population, especially in the setting of respiratory failure.