Protamine Reaction v1
I. DESCRIPTION: Following cardiopulmonary bypass with heparin anticoagulation, protamine sulfate is used to neutralize the effects of heparin and reverse anticoagulation. Currently […]
HIT
Heparin Induced Thrombocytopenia I. DESCRIPTION: Heparin induced thrombocytopenia (HIT) and heparin induced thrombocytopenia thrombosis syndrome (HITTS) are immune mediated complications of heparin […]
Cold Agglutinins v.1
I. BACKGROUND: Hypothermic cardiopulmonary bypass with the use of cold blood cardioplegia carries with it the risk of red cell agglutination caused […]
AT3 Deficiency v.1
Antithrombin III (AT III) is a plasma glycoprotein with a molecular weight of 58,000 daltons. AT III deficiency may be noticed when […]
Jehovah’s Witness v.1
JEHOVAH’S WITNESSES Jehovah’s Witness patients are at increased risk for morbidity and mortality associated with blood loss due to their refusal, on […]
Malignant Hyperthermia v 1
I. PATHOPHYSIOLOGY: Malignant hyperthermia (MH) is a pharmacogenetic disorder characterized by a fulminant hypermetabolic reaction of skeletal muscle induced by volatile inhalational […]