Coagulopathies
Coagulopathies The most common cause of intraoperative coagulopathy is thrombocytopenia secondary to hemodilution. Thrombocytopenia is a condition where the circulating platelet count […]
Common Pathway (Coagulation)
The endpoint of activity for both the extrinsic and intrinsic pathways for coagulation is the activation of factor X. Reactions beyond this […]
Jehovah’s Witness v.1
JEHOVAH’S WITNESSES Jehovah’s Witness patients are at increased risk for morbidity and mortality associated with blood loss due to their refusal, on […]
Malignant Hyperthermia v 1
I. PATHOPHYSIOLOGY: Malignant hyperthermia (MH) is a pharmacogenetic disorder characterized by a fulminant hypermetabolic reaction of skeletal muscle induced by volatile inhalational […]
Coagulopathies & Treatment
Coagulopathies & Treatment The most common cause of intraoperative coagulopathy is thrombocytopenia (decrease in platelet count) secondary to hemodilution. Blood loss that […]
Activated Clotting Time (ACT)
Activated Clotting Time (ACT) The ACT is a standardized measurement of the patients procoagulation or anticoagulation level. The unit of measurement is […]
Hemostasis Assays [v.1]
Partial Thromboplastin Time (Activated) The activated partial thromboplastin time (aPTT) is test that overlaps the prothrombin time (both evaluate the common pathway), […]
Heparin (v.1)
HEPARIN ONSET: Maximal at 1 minute past atrial delivery: Measured at radial artery. Note: 10-20% reduction in svr without affecting […]
Coagulation Cascade (V.1)
Intrinsic Pathway The coagulation cascade is initiated when blood becomes traumatized by exposure to a foreign surface. An example of this […]