Transfusion of Leukocyte-Depleted RBCs Is Independently Associated With Increased Morbidity After Pediatric Cardiac Surgery
Transfusion of leukocyte-depleted RBCs within the first 48 hrs of PICU stay after cardiac surgery is independently associated with prolonged duration of mechanical ventilation.
Mini-Extracorporeal Circulation Minimizes Coagulation Abnormalities and Ameliorates Pulmonary Outcome in Coronary Artery Bypass Grafting Surgery
Our study suggests that MECC induces less coagulation disorders, leading to lower postoperative blood loss and better postoperative lung function. This approach may be advantageous in high-risk patients.
Blood Product Conservation is Associated with Improved Outcomes and Reduced Costs after Cardiac Surgery
The purpose of this investigation was to determine whether a multi-institutional effort to reduce blood product use affects postoperative events aftercardiac surgical operations and to determine the influence of perioperative transfusion on risk-adjusted outcomes.
Perfusion Tubing: Standardized or Modify?
I applaud our adult colleagues in trying to do what is best for the patient even if standardized tubing packs have to be modified resulting in higher prices as some would argue.
Meta-Analysis of the Studies of Bleeding Complications of Platelets Pathogen-Reduced with the Intercept System
Treatment with Intercept may increase the risk of all and clinically significant (albeit not severe) bleeding complications in RCTs maintaining a platelet count of ≥10×10(9) or ≥20×10(9)/l through increased platelet transfusions.
Transfusion of Older Stored Blood and Risk of Death: A Meta-Analysis
Based on available data, use of older stored blood is associated with a significantly increased risk of death.
How we Provide Transfusion Support for Neonatal and Pediatric Patients on Extracorporeal Membrane Oxygenation
In this article, we describe our protocol for transfusion support for ECMO and potential ECMO patients.
Impact of Red Blood Cell Transfusion on Global and Regional Measures of Oxygenation
This article will review fundamental aspects of oxygen delivery and extraction, and the effects of red blood cell transfusion on tissue oxygenation as well as the microcirculation.
High Mortality Associated with Intracardiac and Intrapulmonary Thromboses after Cardiopulmonary Bypass
In this retrospective review, we attempt to identify risk factors and propose possible mechanisms of thromboses after cardiopulmonary bypass (CPB).
Influence of Hemodynamic Variations on the Pharmacokinetics of Landiolol in Patients Undergoing Cardiovascular Surgery
We investigated the influence of hemodynamic variation and the following hepatocirculatory changes after systemic heparinization on the pharmacokinetics of landiolol in patients undergoing cardiovascular surgery under cardiopulmonary bypass.
Formation of Intracardiac Thrombus During Cardiopulmonary Bypass Despite Full Heparinization and Adequate Activated Clotting Time: A Case Report
This case alerts the anesthesiologists of possible thrombus formation despite full heparinization during cardiac surgery and the importance of a comprehensive echocardiography examination.
An Evaluation of Factors Affecting Activated Coagulation Time
All these observations suggest that failure to achieve an adequate ACT is, in general, not an indicator of AT deficiency but could be affected by high platelet counts and low hemoglobin levels.