Tranexamic Acid in Remote Damage Control Resuscitation
In this paper, the authors review the current state of the art for tranexamic acid (TXA) and its potential benefits to those patients who are in need of a massive transfusion. Specifically addressed are its biologic and pharmacologic properties, as well the results of a number of recent studies.
An Observational Study of the Fresh Frozen Plasma: Red Blood Cell Ratio in Postpartum Hemorrhage
In this retrospective study, a higher FFP:RBC ratio was associated with a lower requirement for advanced interventional procedures in the setting of postpartum hemorrhage.
Massive Bleeding and Massive Transfusion
This review surveys current literature on fluid resuscitation, blood transfusion, and hemostatic agents currently used during massive hemorrhage in order to optimize patients'blood and coagulation management in emergency medical aid.
TEG® and ROTEM® in Trauma: Similar Test but Different Results
This review evaluates the comparability between TEG and ROTEM and performs a descriptive review of the parameters utilized in each test in adult trauma patients.
Potential Value of Transfusion Protocols in Cardiac Surgery
This article reviews the current literature between 1995 and 2012 dealing with transfusion protocols in cardiovascular surgery. The 16 studies fitting these search criteria have evaluated the impact of the implementation of ROTEM/TEG based coagulation management algorithms on transfusion requirement and outcome in overall 8507 cardiovascular surgical patients.
Hypercoagulation Assessed by Thromboelastography is Neither Related to Infarct Size nor to Clinical Outcome After Primary Percutaneous Coronary Intervention
We investigated the relationship between coagulation assessed by thromboelastography (TEG) and myocardial damage in ST-segment elevation myocardial infarction (STEMI).
Monitoring Incomplete Heparin Reversal and Heparin Rebound After Cardiac Surgery
In this study we assessed the incidence of incomplete heparin reversal and heparin rebound after cardiac surgery with cardiopulmonary bypass (CPB) and the ability of the activated coagulation time (ACT) and thromboelastography (TEG) to detect these phenomena. DESIGN:
Impact of Retransfusion of Blood Processed in Cell-Saver on Coagulation Versus Cardiopulmonary Bypass: A Prospective Observational Study Using Thromboelastography
In this study we compared an impact of retransfusion of blood processed in cell-saver (CS) with that of cardiopulmonary bypass (CPB) on blood coagulation in patients undergoing cardiac surgery.
Innate Immune Activation after Transfusion of Stored Red Blood Cells
In this narrative review, we explore the hypothesis that prolonged RBC storage results in elaboration of substances which may function as danger associated molecular pattern molecules that activate the innate immune system with consequences unfavorable to healthy homeostasis.
Role of Cytokines in Cardiopulmonary Bypass-Induced Ventricular Dysfunction in a Porcine Model (EP Video)
Craig Vocelka discusses the role of cytokines during CPB-induced LV dysfunction in the porcine model (18:16 minutes).
Effect of Intra-operative Nadir Hematocrit During Cardiac Surgery: The Michigan Experience (EP Video)
Donald Likosky discusses the effect of Nadir hematocrit during cardiac surgery from the Michigan database (9:53 minutes).
Changes in ACTs and Dose Requirements of Unfractionated Heparin During Adult Cardiopulmonary Bypass Pre and Post FDA Mandated Changes: A Retrospective Chart Review (EP Video)
Amanda Deyo discusses the need to change Heparin dosing through a retrospective chart review (10:53 minutes).