Extracellular Vesicles in Autologous Cell Salvaged Blood in Orthopedic Surgery
Retransfusate contains negligible amounts of potentially thrombogenic EVs from platelet and monocytic origin. Frequent EVs from erythrocytes may indicate red blood cell destruction and/or activation during autologous cell salvage. Further research is needed to investigate the clinical relevance of EVs from salvaged red blood cells.
Perioperative Cryoprecipitate Waste Reduction
These results demonstrate that utilizing educational initiatives for optimization of blood product management can reduce unnecessary ordering, transfusions, and wastage; an outcome that could ultimately reduce costs.
Heparin-Free Lung Transplantation on Venovenous Extracorporeal Membrane Oxygenation Bridge
Despite the limited patient population, such an approach relies on a strong rationale and may be beneficial for managing ECMO bridging to LuTX. Prospective studies are necessary to confirm the validity of our strategy.
Blood Loss Kinetics During the First 12 Hours After On-Pump Cardiac Surgical Procedures
The hourly rate of chest tube blood loss seems to be relevant to predict, within the first postoperative hours after cardiac surgical procedures, major bleeding at 12 postoperative hours. Early detection of blood loss may help to improve a patient’s blood conservation strategy because it may prompt preemptive treatments.
Thromboelastography During Rewarming for Management of Pediatric Cardiac Surgery Patients
Lower MA during rewarming is associated with increased risk of perioperative bleeding. In patients with rewarming MA<45mm, intraoperative platelet transfusion may reduce the risk of subsequent bleeding. Individualized platelet transfusion therapy based on rewarming TEG may reduce the risk of bleeding while minimizing unnecessary platelet transfusion.
Intra-Operative Autologous Blood Donation for Cardiovascular Surgeries in Japan: A Retrospective Cohort Study
Intra-operative autologous blood donation could reduce the transfusion rate or amount of red blood cells and fresh frozen plasma for patients undergoing index cardiovascular surgery and could be an effective blood transfusion strategy in cardiovascular surgery for Japanese patients.
Comparison of Anticoagulation Strategies in Patients Requiring Venovenous Extracorporeal Membrane Oxygenation: Heparin Versus Bivalirudin
Patients receiving bivalirudin for systemic anticoagulation on venovenous extracorporeal membrane oxygenation experienced a decrease in the number of extracorporeal membrane oxygenation circuit-related thrombotic events as well as a significant decrease in volume of blood products administered.
Blood Transfusion Trends by Disease Category in The United States, 2000 to 2014
Blood transfusion rates decreased from 2011 to 2014 in the United States. This decline occurred in most disease categories, which points towards broad strategies like patient blood management systems and disease specific improvements like changes in surgical techniques being effective.
Intraoperative Cell Salvage
By reading this article you should be able to: •Discuss why it may be beneficial to avoid allogeneic (donor) transfusion. •List the benefits that intraoperative cell salvage (ICS) can provide. •Identify when ICS usage is both appropriate and safe. •Explain the complications of ICS. •Describe areas of controversy relating to the use of ICS.
Viscoelastic Coagulation Monitor as a Novel Device to Assess Coagulation at the Bedside. A Single-Center Experience During the COVID-19 Pandemic
In conclusion, VCM provided reliable results in COVID-19 patients and was easy to perform with minimal training at the bedside.
Cardiopulmonary Bypass in A Child with Severe Factor XII Deficiency
We report the case of a 14.7 kg girl undergoing CPB with a pre-admission FXII concentration of <1% and aPTT >200 seconds. The child was transfused with fresh-frozen plasma to replenish FXII, allowing safe ACT monitoring of heparin anticoagulation throughout CPB.
Red Blood Cell Transfusion Requirements for Patients on Extracorporeal Membrane Oxygenation
Patients without clinical bleeding still required transfusion, with higher rates observed with VA- than VV-ECMO. Transfusion requirements dramatically increased when patients developed various bleeding complications and had a significant impact on 30-day mortality rate.