Cold Agglutinins in Patients undergoing Cardiac Surgery requiring Cardiopulmonary Bypass
Cold agglutinins (CA) are circulating autoantibodies present in most humans.
Association of Plasma Dilution with Cardiopulmonary Bypass-Associated Bleeding and Morbidity
Patient morbidity and likelihood of transfusion were associated with calculated plasma protein concentrations below 45% of baseline.
Blood Conservation Strategies in Cardiac Surgery: More is Better
Recent data show that up to 50% of heart procedures require blood transfusion, which can have adverse long- and short-term outcomes for the patient. This led to the updated 2011 Society of Thoracic Surgery (STS)/Society of Cardiovascular Anesthesiologists (SCA) guidelines in an attempt to adopt more effective blood conservation techniques.
Transfusion of 1 and 2 Units of Red Blood Cells is Associated with Increased Morbidity and Mortality
Transfusion of as little as 1 or 2 units of RBCs is common and is significantly associated with increased morbidity and mortality
Transfusion Practice varies Widely in Cardiac Surgery: Results from a National Registry
Variation in transfusion of all components and large volume RBC was identified,
Blood Transfusion during versus after Cardiopulmonary Bypass is Associated with Postoperative Morbidity in Neonates undergoing Cardiac Surgery
multivariate analyses confirmed an independent association of transfusion On-CPB with an adverse clinical outcome.
Platelet Dysfunction as Measured by a Point-of-Care Monitor is an Independent Predictor of High Blood Loss in Cardiac Surgery
Excessive bleeding carries a heavy burden of illness in cardiac surgery. Although platelet dysfunction is considered to be an important cause, it is not routinely measured. Our objective was to explore the relationship between platelet dysfunction and blood loss in cardiac surgery.
The Operating Surgeon Is an Independent Predictor of Chest Tube Drainage Following Cardiac Surgery
Bleeding into the chest is a major cause of blood transfusion and adverse outcomes following cardiac surgery. The authors investigated predictors of bleeding following cardiac surgery to identify potentially correctable factors.
Initial Experience with Internal Mammary Artery Harvesting with the da Vinci Surgical System for Minimally Invasive Direct Coronary Artery Bypass
We evaluated the feasibility of off-pump minimally invasive direct coronary artery bypass (MIDCAB) in combination with robotic harvesting of the left internal mammary artery (LIMA).
Percutaneous Mitral Valve Repair with the MitraClip: Early Results from the MitraClip Asia-Pacific Registry (MARS)
Percutaneous MitraClip therapy has been shown to be safe and efficacious in mitral regurgitation (MR). Our aim was to describe early outcomes in patients from the Asia-Pacific region.
Comparison of Two Tranexamic Acid Dose Regimens in Patients Undergoing Cardiac Valve Surgery
Tranexamic acid (TA), a synthetic antifibrinolytic drug, has been shown to reduce postoperative bleeding and the need for allogeneic blood transfusion in cardiac surgery. However, the optimal dose regimen of TA is still under debate. The aim of this study was to evaluate whether a lower-dose TA regimen produced equivalent efficacy to its higher-dose counterpart in reducing postoperative bleeding and transfusion needs.
The Effect of Tranexamic Acid in Blood Loss and Transfusion Volume in Adolescent Idiopathic Scoliosis Surgery: A Single-Surgeon Experience
Tranexamic acid (TXA) has been shown to decrease blood loss in cardiac and joint surgery. Few studies have examined its use in pediatric spine surgery, and the results are inconsistent. The aim of this study was to determine whether TXA decreases intraoperative blood loss and transfusion requirements in adolescent idiopathic scoliosis patients undergoing posterior spinal fusion by a single surgeon.