Platelet Rich Plasma and Knee Surgery
In the last fifteen years, the field of regenerative medicine is witnessing a boost of autologous blood-derived platelet rich plasma products (PRPs) application to effectively mimic and accelerate the tissue healing process.
Mesenchymal Stem Cells for Cardiac Regenerative Therapy: Optimization of Cell Differentiation Strategy
In this review, we will focus on the recent progress on mesenchymal stem cells (MSCs) derived cardiomyocytes for cardiac regeneration after myocardial infarction (MI).
Hemoglobin Optimization and Transfusion Strategies in Patients Undergoing Cardiac Surgery
Although red blood cells (RBCs) transfusion is sometimes associated with adverse reactions, anemia could also lead to increased morbidity and mortality in high-risk patients.
The Effect of Aspirin on Bleeding and Transfusion in Contemporary Cardiac Surgery
The purpose of this study was to investigate preoperative aspirin use and its effect on bleeding and transfusion in cardiac surgery.
Haemodynamic Goal-Directed Therapy in Cardiac and Vascular Surgery. A Systematic Review and Meta-Analysis
The purpose of the present meta-analysis is to determine the effects of perioperative haemodynamic goal-directed therapy on mortality and morbidity in cardiac and vascular surgery.
Platelet-Rich Fibrin Promotes an Accelerated Healing of Achilles Tendon When Compared to Platelet-Rich Plasma in Rat
We compared the effect of using platelet-rich plasma(PRP) and platelet-rich fibrin (PRF) in repairing rat Achilles tendon.
TEG®- or ROTEM®-Based Individualized Goal-Directed Coagulation Algorithms: Don’t Wait–Act Now
TEG® and ROTEM® allow prediction of massive transfusion requirement and mortality, and creation of goal-directed, individualized coagulation algorithms that may improve patient outcome.
Platelet-Rich Plasma as a Treatment for Chronic Patellar Tendinopathy: Comparison of a Single Versus Two Consecutive Injections
Platelet-rich-plasma is increasingly used in chronic patellar tendinopathy. Ideal number of PRP injections needed is not yet established. This study compares the clinical outcomes of a single versus two consecutive PRP injections.
Safe Anticoagulation When Heart and Lungs are “On Vacation”
Circulation and oxygenation of blood outside the body is commonly required during complex surgical interventions involving coronary pulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO).
Successful Use of a Military Haemostatic Agent in Patients Undergoing Extracorporeal Circulatory Assistance and Delayed Sternal Closure
We report the successful control of bleeding in two patients who underwent post-cardiotomy extracorporeal circulatory support (ECMO) and then developed life-threatening bleeding due to severe coagulopathy.
Management of Anticoagulation and Hemostasis for Pediatric Extracorporeal Membrane Oxygenation
Compared to in situ vascular physiology where pro and anti-hemostatic processes are in balance to maintain hemostasis, the use of ECMO in a critically ill child increases the risk of hemorrhagic or thromboembolic events due to a perturbation in the balance inherent of this complex system.
Use of a Fixed, Body Weight-Unadjusted Loading Dose of Unfractionated Heparin for Extracorporeal Cardiopulmonary Resuscitation
A major complication of Extracorporeal cardiopulmonary resuscitation (ECPR) is bleeding; however, the optimal initial heparin dose and activated coagulation time (ACT) remain unknown. The aim of this study was to assess the appropriateness of our initial anticoagulation protocol.