Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery
The effect of a restrictive versus liberal red-cell transfusion strategy on clinical outcomes in patients undergoing cardiac surgery remains unclear.
Coronary Artery Bypass Surgery in End-Stage Renal Disease Patients
This review discusses the epidemiology, vascular pathology and current treatment options in patients with end-stage renal disease requiring coronary revascularization.
Extracorporeal Ultrafiltration for Fluid Overload in Heart Failure
More than 1 million heart failure hospitalizations occur annually, and congestion is the predominant cause. Rehospitalizations for recurrent congestion portend poor outcomes independently of age and renal function.
Effects of Cerebral Near-Infrared Spectroscopy on the Outcome of Patients Undergoing Cardiac Surgery: A Systematic Review of Randomised Trials
Goal-directed optimisation of cerebral oxygenation using near-infrared spectroscopy (NIRS) during cardiopulmonary bypass is widely used. We tested the hypotheses that the use of NIRS cerebral oximetry results in reductions in cerebral injury (neurocognitive function, serum biomarkers), injury to other organs including the heart and brain, transfusion rates, mortality and resource use.
Association Between Platelet Count and Postoperative Blood Loss in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass and Fresh Frozen Plasma Administration Guided by Thromboelastometry
Coagulopathy after cardiopulmonary bypass (CPB) is caused by multiple factors, including reduced coagulation factors and a low platelet count.
Prediction of Postoperative Blood Loss Using Thromboelastometry in Adult Cardiac Surgery: Cohort Study and Systematic Review
The aim was to evaluate the predictive value of thromboelastometry for postoperative blood loss in adult cardiac surgery with cardiopulmonary bypass.
Point-of-Care Washing of Allogeneic Red Blood Cells for the Prevention of Transfusion-Related Respiratory Complications (WAR-PRC): A Protocol for a Multicenter Randomised Clinical Trial in Patients Undergoing Cardiac Surgery
Point-of-care (POC) washing of allogeneic RBCs may remove biological response modifiers (BRMs), thereby mitigating their impact on post-transfusion respiratory complications.
Thromboelastography for Predicting Bleeding in Patients with Aortic Stenosis Treated with TAVI
Bleeding complications are frequent and independently impact mortality after TAVI. Thromboelastography (TEG) measures viscoelastic properties of clot formation and is currently best known for perioperative management to reduce blood transfusion in cardiac surgery.
Use of a Flowable Haemostat Versus an Oxidised Regenerated Cellulose Agent in Primary Elective Cardiac Surgery: Economic Impact from a UK Healthcare Perspective
We investigated the economic impact of the use of a flowable haemostatic agent (Floseal) compared with non-flowable oxidised regenerated cellulose (ORC) agent in primary elective cardiac surgeryfrom the perspective of the UK National Health Service (NHS).
Diagnostic and Therapeutic Medical Devices for Safer Blood Management in Cardiac Surgery: Systematic Reviews, Observational Studies and Randomised Controlled Trials
This study evaluated the clinical effectiveness and cost-effectiveness of medical devices used as diagnostic and therapeutic tools for the management of anaemia and bleeding in cardiac surgery.
Transcatheter or Surgical Aortic Valve Replacement in Patients with Advanced Kidney Disease: A Propensity Score-Matched Analysis
Transcatheter aortic valve replacement (TAVR) is an alternative for surgically inoperable patients with severe aortic stenosis. Advanced kidney disease may significantly affect outcomes in patients treated with TAVR and surgical aortic valve replacement (SAVR).
Single Dose Del Nido Cardioplegia in Minimally Invasive Aortic Valve Surgery
Del Nido cardioplegia (DC) offers prolonged cardiac protection with single dose administration and has been shown to be safe in adult CABG surgery. We set out to evaluate the efficacy of cardiac protection and clinical outcomes of del Nido cardioplegiaversus standard blood cardioplegia (BC) in minimally invasive aortic valve surgery.