Hemostasis Management of Patients Undergoing Emergency Cardiac Surgery After Ticagrelor Loading
Pharmacologic Inhibition of platelet P2Y12 receptors has become the mainstay of therapy in the management of acute coronary syndrome.
Viscoelastic Blood Tests Use in Adult Cardiac Surgery: Meta-Analysis, Meta-Regression, and Trial Sequential Analysis
This study demonstrated that the use of VE assays in cardiac surgical patients is effective in reducing allogenic blood products exposure, postoperative bleeding at 12 and 24 hours after surgery, and the need for redo surgery unrelated to surgical bleeding.
Comparative Pharmacological Profiles of Various Bovine, Ovine, and Porcine Heparins
These studies have demonstrated that OMH and PMH have comparable anticoagulant and antiproteases activities. However, BMH exhibited somewhat a lower potency compared to OMH and PMH in functional assays.
Post-operative Blood Loss is Higher Among African American Neonates Undergoing Open-heart Surgery with Cardiopulmonary Bypass for CHD
Among neonates with CHD undergoing open-heart surgery with cardiopulmonary bypass, African-American race is independently associated with greater chest tube output over the first 24 hours post-operatively.
Microvascular Alterations During Cardiac Surgery Using a Heparin or Phosphorylcholine-Coated Circuit
The use of an HC circuit is associated with better preservation of the endothelial glycocalyx compared with PC circuits, whereas microcirculatory perfusion was disturbed equally in both groups.
Retrograde Autologous Priming in Surgery of Thoracic Aortic Aneurysm
RAP is a safe and easy method to reduce RBC transfusion in TAA surgery without any adverse effects on the clinical outcome.
Comparative Analysis of Prothrombin Complex Concentrate and Fresh Frozen Plasma in Coronary Surgery
These results suggest that the use of PCC compared with FFP may reduce the need of blood transfusion after CABG.
Gender-based Differences in Platelet Function and Platelet Reactivity to P2Y12 Inhibitors
Our findings confirm that women have a larger platelet count than men, and that this is associated to a trend towards a higher platelet reactivity.
Safety and Efficacy of Tranexamic Acid in Paediatric Cardiac Surgery: Study Protocol for a Double-Blind Randomised Controlled Trial
An initial retrospective study suggested that tranexamic acid (TXA) administration increased the incidence of seizures in paediatric patients undergoing cardiac surgery.
Comparison of Two Doses of Tranexamic Acid in Adults Undergoing Cardiac Surgery with Cardiopulmonary Bypass
A high dose of TA does not reduce incidence of blood product transfusion up to day 7, but is more effective than a low dose to decrease transfusion needs, blood loss, and repeat surgery.
Four-Factor Prothrombin Complex Concentrate for the Reversal of Direct Oral Anticoagulants
Based on the results thus far, the use of 4-factor PCC may be a good treatment option in patients requiring DOAC reversal.
Cold Agglutinins and Cardiac Surgey: a Case Report
Cold agglutinins (CA) are autoantibodies whose clinical significance depends upon titer and thermal amplitude.