Net Prime Volume Is Associated with Increased Odds of Blood Transfusion
Our findings reinforce the importance of efforts to reduce the net CPB prime volume. Based on these findings and other supporting evidence, the net prime volume should be adopted as a national quality measure.
Heparin Sensitivity and Postoperative Blood Loss in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
Postoperative blood loss is related to heparin sensitivity in patients undergoing cardiac surgery, and the moderately sensitive patients have the least postoperative bleeding.
Application of Piezo-Based Measuring System for Evaluation of Nucleic Acid-Based Drugs Influencing the Coagulation
The obtained results showed that the established PIEZ is capable to dynamically measure the hemostasis status in whole blood and can be applied to analyze nucleic acid-based drugs influencing the coagulation.
Outcomes of Cardiovascular Surgery Utilizing Heparin versus Direct Thrombin Inhibitors in Cardiopulmonary Bypass in Patients with Previously Diagnosed HIT
DTI appears to be safe in selected patients undergoing CPB after a diagnosis of HIT, and was not associated with higher rates of 30-day mortality, thrombosis, or hemorrhage.
The Prophylactic Use of Fibrinogen Concentrate in High‐Risk Cardiac Surgery
This randomized, controlled trial demonstrates that point‐of‐care guided and prophylactic treatment with fibrinogen concentrate does not reduce transfusion of blood products in a setting of unexpectedly low transfusion rate as tested in this cohort, but may improve coagulation parameters in the setting of high‐risk cardiac surgery.
Single Ventricle Physiology Patients and Coagulation Abnormalities: Is There a Relationship With Hemodynamic Data and Postoperative Course? A Pilot Study
Abnormalities in coagulation parameters are common in SV patients. Coagulation abnormalities constitute a preoperative risk factor and affect postoperative course.
Platelet Administration During Cardiopulmonary Bypass in Neonates: A Universal Therapy Applied in a Novel Way
Improved intraoperative and postoperative hemostasis was observed in neonates given platelets during the rewarming phase of cardiopulmonary bypass.
Antithrombin Supplementation in Adult Patients Receiving Extracorporeal Membrane Oxygenation
Therapeutic anticoagulation occurred more frequently following antithrombin supplementation; however, this difference was not statistically significant. More bleeding events occurred following antithrombin supplementation while observing an increase in platelet transfusions.
Clinical Utility of the Quantra® Point‐of‐care Haemostasis Analyser During Urgent Cardiac Surgery
We have shown that point‐of‐care testing using the novel Quantra system provides useful data for guiding transfusion management.
A Multicenter Comparison of 2 Point-of-Care Activated Clotting Time Test Systems
Activated clotting time (ACT) is used to monitor unfractionated heparin anticoagulation during invasive procedures such as percutaneous coronary or electrophysiology interventions.
Transfusing Platelets During Bypass Rewarming in Neonates Improves Postoperative Outcomes: A Randomized Controlled Trial
Platelet transfusion during the rewarming phase of neonatal cardiac surgery was associated with reduced bleeding and improved postoperative outcomes, compared to platelets given after coming off bypass.
Thrombocytopenia After Cardiopulmonary Bypass is Associated with Increased Morbidity and Mortality
Thrombocytopenia is a risk factor for morbidity and mortality in critically ill patients, and is common following cardiopulmonary bypass (CPB).