Thromboelastometry And A Hemostasis Management System are Most Beneficial for Guiding Hemostatic Therapy in Cardiac Surgery Patients with a Euroscore II of ≥1.83%: A Randomized Controlled Two-Step Trial
POC testing is beneficial for cardiac surgery patients with a EuroSCORE II of ≥1.83%.
Application of Goal-Directed Therapy for the Use of Concentrated Antithrombin for Heparin Resistance During Cardiac Surgery
Utilization of a goal-directed algorithm for the administration of antithrombin for the treatment of heparin resistance is effective in patients undergoing cardiac surgery.
Hypothermic Circulatory Arrest Induced Coagulopathy: Rotational Thromboelastometry Analysis
Our study confirmed that the amount of perioperative bleeding and intraoperative transfusion were significantly higher in the HCA group. ROTEM analysis would indicate that clot firmness contributed by platelet component is reduced by HCA in cardiac surgery.
Prospective Evaluation of a Blood Transfusion Protocol for Patients Undergoing Cardiac Operations
During a prospective evaluation of blood transfusion protocols, a risk-adjusted analysis demonstrated a reduction in transfusions despite poor protocol compliance.
Anticoagulation Management During Pulmonary Endarterectomy With Cardiopulmonary Bypass and Deep Hypothermic Circulatory Arrest
This study shows a wide variation in individual heparin sensitivity in patients undergoing pulmonary endarterectomy with deep hypothermic circulatory arrest.
Feasibility Study of a Novel Method of Concentrating Fresh Frozen Plasma by Hemoconcentrating Filter Outside Cardiopulmonary Bypass
We invented a novel method of concentrating FFP by applying a hemoconcentrating filter directly to FFP to both minimize volume and avoid affecting platelet function.
A Single Preoperative Dose of Tranexamic Acid Reduces Perioperative Blood Loss
Preoperative intravenous TXA reduced perioperative blood loss and transfusion requirements in a variety of surgical disciplines without increasing the risk of thromboembolic events. Therefore, it should be considered for prophylactic use in surgery to reduce operative bleeding.
Comparison of Three Autotransfusion Devices for Utilization in the Pediatric Population
Each device proved effective within our pediatric population.
Effects of Cardiopulmonary Bypass with Low-priming Volume on Clinical Outcomes in Children Undergoing Congenital Heart Disease Surgery
The usage of PRBCs in CPB with low-priming volume decreased significantly, but the postoperative Hb concentration and platelet count could still be maintained at a high level, improving the use efficiency of PRBCs. CPB with low-priming volume did not affect the postoperative recovery of patients, so it is worthy of continuous promotion and optimization.
Standards and Best Practice for Acute Normovolemic Hemodilution: Evidence-based Consensus Recommendations
The recommendations developed by this expert panel may help guide the management and inclusion of ANH as an evidence and consensus-based blood conservation modality.
Influence of Hemoadsorption during Cardiopulmonary Bypass on Blood Vesicle Count and Function
Additional artificial surfaces to the CPB-circuit introduced by the use of the HA device showed no effect on circulating MV count and function in these patients. Larger studies are needed to assess and clarify the effect of HA on circulating vesicle counts and function.
Thromboelastographic Results and Hypercoagulability Syndrome in Patients With Coronavirus Disease 2019 Who Are Critically Ill
Our findings suggest that alterations of diagnostic and prophylactic treatment guidelines may be critical for the successful treatment of coagulopathies associated with COVID-19.