Effects of Cardiac Surgery and Salvaged Blood Transfusion on Coagulation Function Assessed by Thromboelastometry
Salvaged blood transfusion of more than 18.5% whole blood volume may impair coagulation function particularly in patients with lower FIBTEM-MCF before and after cardiac surgery.
Factors Influencing Activated Clotting Time Following Heparin Administration for the Initiation of Cardiopulmonary Bypass
Old age, heart failure, and lower platelet counts affected heparin activity. The dose of heparin should be considered in those patients to reach the target ACT.
The Blood Protective Effect of Autologous Platelet Separation in Aortic Dissection
The intraoperative auto transfusion of platelets significantly reduced the volume of allogeneic platelet transfusion after the operation for aortic dissection, which has a significant blood protective effect.
Antithrombin Use During Pediatric Cardiac Extracorporeal Membrane Oxygenation Admission: Insights from A National Database
Together, these results reinforce that antithrombin may not be indicated for all pediatric extracorporeal membrane oxygenation patients.
Extracorporeal Life Support in Hemorrhagic Conditions: A Systematic Review
The use of ECLS for temporary circulatory or respiratory support in critical patients with refractory hemorrhagic shock appears feasible considering tailored ECMO management strategies.
Evaluation of Point-of-Care ACT Coagulometers and Anti-Xa Activity During Cardiopulmonary Bypass
This suggests that ACT devices should not be used interchangeably, but cut-off values for safe anticoagulation during cardiopulmonary bypass should be determined for each type of device, particularly when switching supplier.
Selling the Role of Salvage: Cell Salvage Past and Present
Despite the body of evidence to support the use of salvaged blood for transfusion, hesitation around its use still persists, with staff apprehension around set up of cell salvage equipment and general underestimation of intraoperative blood loss being key factors in its underuse.
Determinants of Hospital Variability in Perioperative Red Blood Cell Transfusions During Coronary Artery Bypass Graft Surgery
The results suggest that variation in center-level red blood cells transfusion cannot be explained by patient and procedural factors alone. Investigating organizational culture and programmatic infrastructure may be necessary to better understand variation in transfusion practices.
Association Between Transfusion of Blood Products and Acute Kidney Injury Following Cardiac Surgery
Transfusion of all blood products in a dose‐dependent manner increased the risk for AKI. However, in multivariate analysis combining all blood products, only red blood cell transfusion remained significantly associated with AKI development.
A 0.6-Protamine/Heparin Ratio in Cardiac Surgery is Associated with Decreased Transfusion of Blood Products
A 0.6/1-protamine/heparin ratio after weaning from CPB is associated with a significantly reduced 12-h postoperative blood loss and blood components transfusion.
Use of Coagulation Point-of-Care Tests in the Management of Anticoagulation and Bleeding in Pediatric Cardiac Surgery: A Systematic Review
At present, literature data are too weak to define POCTs as a “gold standard” for the treatment of perioperative bleeding in pediatric cardiac surgery.
Hematologic Concerns in Extracorporeal Membrane Oxygenation
This review aims to broadly introduce modern ECMO practices, circuit designs, circuit materials, hematologic complications, transfusion‐related considerations, age‐ and size‐related differences, and considerations for choosing outcome measures.