Benefits and Risks of Aprotinin Use During Cardiac Surgery
Aprotinin is a serine protease inhibitor with antithrombotic, antifibrinolytic, and antiinflammatory effects.
International Variation in the Use of Blood Transfusion in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes
The purpose of this study was to determine international patterns of blood transfusion in patients with acute coronary syndrome (ACS).
The Effect of Preprocessing Stored Red Blood Cells on Neonates Undergoing Corrective Cardiac Surgery
This study compared the effect of unprocessed and processed packed red blood cells (PRBCs) with the continuous autotransfusion system (CATS) during neonate heart surgery.
Effect of Platelet-Rich Plasma on the Early Bone Formation Around Ca-P-Coated and Non-Coated Oral Implants in Cortical Bone
The purpose of the present study was to investigate the effect of local application of platelet-rich plasma (PRP) on the early healing of cortical bone around Ti implants with two different surface configurations.
Periodontal Tissue Regeneration with Adipose-Derived Stem Cells
In this study, we sought to determine whether adipose-derived stem cells (ASCs) can promote periodontal tissue regeneration as well. ASCs were isolated from a Wistar rat, passaged twice, mixed with platelet-rich plasma (PRP) obtained from inbred rats, and implanted into the periodontal tissue defect that had been generated in the test rats.
Increased Mortality, Postoperative Morbidity, and Cost After Red Blood Cell Transfusion in Patients Having Cardiac Surgery
To inform decisions about transfusion, we aimed to quantify associations of transfusion with clinical outcomes and cost in patients having cardiac surgery.
The Cardiotomy Trial: A Randomized, Double-Blind Study to Assess the Effect of Processing of Shed Blood During Cardiopulmonary Bypass on Transfusion and Neurocognitive Function
We sought to evaluate the effects of cardiotomy blood processing on blood product use and neurocognitive functioning after cardiac surgery.
Evolution of Adverse Changes in Stored RBCs
We analyzed changes occurring during RBC storage focusing on RBC deformability, RBC-dependent vasoregulatory function, and S-nitrosohemoglobin (SNO-Hb), through which hemoglobin (Hb) O2 desaturation is coupled to regional increases in blood flow in vivo (hypoxic vasodilation).
Association of RBC Transfusion With Mortality in Patients with Acute Lung Injury
We assessed the effect of RBC transfusion on in-hospital mortality in patients with acute lung injury (ALI).
A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care
To determine whether a restrictive strategy of red-cell transfusion and a liberal strategy produced equivalent results in critically ill patients, we compared the rates of death from all causes at 30 days and the severity of organ dysfunction.
Perioperative Blood Management – A Long Time Coming (Video)
Ty Walker, a perfusionist and expert in blood management, discusses AmSECT's perioperative blood management initiatives.
Bloodless Cardiac Surgery is Associated With Decreased Morbidity and Mortality
We hypothesized that cardiac surgery with perioperative blood transfusion was associated with worse outcomes.