Managing the Coagulopathy Associated with Cardiopulmonary Bypass.
While challenging, the effective management of CPB‐associated coagulopathy can significantly improve patient outcomes.
No Bad Blood — Surviving Severe Anemia Without Transfusion
Physicians who accept the challenges of learning how to treat patients safely and successfully without the traditional safety net of blood transfusion may experience a new level of confidence and expanded opportunities for providing quality care for all patients.
Unit-To-Unit Variability in The Deformability of Red Blood Cells
The present study has demonstrated that storage duration is only one of the factors, and seemingly not even the major one, affecting the PRBCs functionality.
Simple and Effective Blood Salvage Technique for Extracorporeal Membrane Oxygenation Circuit
We describe a simplified technique to salvage the blood in the ECMO circuit that requires no special equipment, is safe, and maximizes blood salvage.
Impact of Intraoperative Cell Salvage on Concentrations of Antibiotics Used for Surgical Prophylaxis
Studies measuring the impact of IOCS on perioperative antibiotic concentrations are warranted.
Effect of Red Blood Cell Storage Duration on Major Postoperative Complications in Cardiac Surgery: A Randomized Trial
This clinical trial, which was stopped at its midpoint owing to enrollment constraints, supports neither the efficacy nor the futility of transfusing either younger or older RBC units.
Hemophilia: A Review of Perioperative Management for Cardiac Surgery
This article provides a narrative review and framework for the perioperative management of patients with hemophilia A and B undergoing cardiac surgery.
The Effect of Levosimendan On Postoperative Bleeding and Blood Transfusion in Cardiac Surgical Patients: A PRISMA-Compliant Systematic Review and Meta-Analysis
This meta-analysis suggested that, peri-operative administration of LEVO was not associated with increased risks of post-operative bleeding and blood transfusion requirement in cardiac surgical patients.
Primary Isolated CABG Restrictive Blood Transfusion Protocol Reduces Transfusions and Length of Stay
A restrictive transfusion protocol reduced blood transfusions and postoperative length of stay without adversely affecting outcomes following isolated primary CABG.
The Incidence and Risk Factors of Hypofibrinogenemia In Cardiovascular Surgery
Intraoperative measurement of SFL is important for detecting hypofibrinogenemia and applying appropriate and prompt transfusion treatment.
The Effect of Antifibrinolytic Use on Intraoperative Cell Salvage: Results from a National Registry of Surgical Procedures
The use of AF has increased each year over the 4-year period in most of the surgical categories, but several have declined. There may be a beneficial effect of AF with lower ICS volumes available for return in a few groups.
Can We Rely on the Activated Clotting Time to Measure Heparin Anticoagulation? A Clinical Evaluation of Two ACT Monitors
ACT monitors demonstrate unacceptable bias differences, combined with wide limits of agreement. The ACT response correlated with hematocrit, but not with the actual heparin concentration.