Fresh Frozen Plasma Is Independently Associated With a Higher Risk of Multiple Organ Failure and Acute Respiratory Distress Syndrome
Blood transfusion is known to be an independent risk factor for mortality, multiple organ failure (MOF), acute respiratory distress syndrome (ARDS), and nosocomial infection after injury.
An Economic Analysis of Costs Associated with Development of a Cell Salvage Program
We present financial information which may be useful to institutions that are considering the addition of a cell salvage service.
Transfusion and Pulmonary Morbidity After Cardiac Surgery
Our objective was to determine the prevalence of pulmonary morbidity related to transfusion and whether TRALI consensus-criteria are applicable to cardiac surgery.
Evaluation of Blood Components Exposed to Coated Arterial Filters in Extracorporeal Circuits
This study evaluates eight biocompatible coatings used for arterial filters and their effects on blood components during circulation.
The Effect of Red Blood Cell Age on Coagulation
Packed red blood cell (PRBC) units stored and unused at community hospitals are transferred to trauma centers near the end of their shelf storage life, because of a higher likelihood of utilization before expiration without consideration of coagulation system effects. This study was conducted to determine if the stored age of PRBC units has an effect on coagulation.
Does Point of Care Prothrombin Time Measurement Reduce the Transfusion of Fresh Frozen Plasma in Patients Undergoing Major Surgery? The POC-OP Randomized-Controlled Trial
Point of care testing of prothrombin time ensures that one major parameter of coagulation is available in the operation theatre within minutes. It is fast, easy to perform, inexpensive and may enable physicians to rationally determine the need for FFP.
Hemostatic Resuscitation for Massive Bleeding: The Paradigm of Plasma and Platelets – A Review of the Current Literature
Continued hemorrhage remains a major contributor of mortality in massively transfused patients and controversy regarding the optimal management exists. Recent studies indicate a possible survival benefit in patients receiving a higher ratio of plasma and platelets (PLTs) to red blood cells (RBCs) than what is recommended in current transfusion guidelines.
Hemofiltration During Cardiopulmonary Bypass Does Not Decrease the Incidence of Atrial Fibrillation After Cardiac Surgery
We hypothesized that hemofiltration during CPB, which may attenuate inflammation, might decrease the incidence of AF after cardiac surgery.
Evidence-Based Transfusion in Cardiac Surgery (Video)
Dr. James Lonquist discusses a multidisciplinary approach to blood management and his experiences in a community hospital setting (58 minutes).
Plasmapheresis and Heparin Reexposure as a Management Strategy for Cardiac Surgical Patients with Heparin-Induced Thrombocytopenia
Heparin-induced thrombocytopenia (HIT) complicates the management of patients presenting for cardiac surgery, because high-dose heparin anticoagulation for cardiopulmonary bypass is contraindicated in these patients.
Acute Transfusion-Associated Lung Injury (TRALI): The Obvious and the Incomprehensible
Acute transfusion-associated lung injury (TRALI) is an acute lung injury associated with and develops within 6 hours after the transfusion of components and blood preparations.
Value of Blood Transfusion in Patients With a Blood Hematocrit of 24% to 30% After Percutaneous Coronary Intervention
Bleeding is a serious complication after percutaneous coronary intervention (PCI).