Meta-Analysis of Clinical Studies of the Purported Deleterious Effects of “Old” (Versus “Fresh”) Red Blood Cells: Are We at Equipoise?
A meta-analysis examined whether the available data support an adequate suspicion that transfusion of old red blood cells (RBCs) is associated with increased mortality, organ failure, infection, prolonged mechanical ventilation, and prolonged stay in the hospital or the intensive care unit.
Hematocrit on Cardiopulmonary Bypass and Outcome After Coronary Surgery in Nontransfused Patients
This study aimed to identify the role of preoperative anemia and hemodilution during cardiopulmonary bypass as determinants of morbidity and mortality after coronary operations.
The Inflammatory Response to Miniaturised Extracorporeal Circulation: A Review of the Literature
This review focuses on the inflammatory and clinical outcomes of using MECC and compares these to conventional cardio-pulmonary bypass (CCPB).
Modified Ultrafiltration with the Hemobag (Video)
Scott Pacheco discusses his clinical experiences with the Hemobag at Palmetto Regional Hospital (27 minutes).
Open Heart Surgery in Patients With Sickle Cell Hemoglobinopathy
The aim of this study was to review retrospectively the perioperative results of patients undergoing cardiac surgery at our institution.
Duration of Red Blood Cell Storage and Outcomes in Pediatric Cardiac Surgery: An Association Found for Pump Prime Blood
The purpose of this study was to investigate the influence of red blood cell storage time prior to transfusion on postoperative morbidity in pediatric cardiac operations.
A Point-of-Care Assessment of the Effects of Desmopressin on Impaired Platelet Function Using Multiple Electrode Whole-Blood Aggregometry in Patients After Cardiac Surgery
In this study, we examined the feasibility of whole blood multiple electrode aggregometry (MEA) for the detection of cardiopulmonary bypass-induced platelet dysfunction and investigated its ability to monitor DDAVP treatment.
Complications of Recombinant Activated Human Coagulation Factor VII
Recombinant factor VIIa (rFVIIa) frequently is used for treatment of life-threatening hemorrhage in trauma.
Near-Infrared Spectroscopy Technique to Evaluate the Effects of Red Blood Cell Transfusion on Tissue Oxygenation
The aim of this study was to evaluate the effects of red blood cell (RBC) transfusions on muscle tissue oxygenation, oxygen metabolism and microvascular reactivity in critically ill patients using near-infrared spectroscopy (NIRS) technology.
Profound Effects of Cardiopulmonary Bypass Priming Solutions on the Fibrin Part of Clot Formation: An Ex Vivo Evaluation Using Rotation Thromboelastometry
Therefore, the authors investigated whether hemodilution with different priming solutions distinctly affects the fibrinogen-mediated step in whole blood clot formation.
Activity-Based Costs of Blood Transfusions in Surgical Patients at Four Hospitals
Determining the cost of supplying patients with blood transfusions requires an in-depth examination of the complex array of activities surrounding the decision to transfuse.
Transfusion and Pulmonary Morbidity After Cardiac Surgery
Our objective was to determine the prevalence of pulmonary morbidity related to transfusion and whether TRALI consensus-criteria are applicable to cardiac surgery.