Perfusionist-Guided Technologies Reduce Blood Utilization and Cost of Cardiac Surgery (Video)
Dr. Russell Stahl discusses the ways perfusionists can have a positive impact on blood utilization and healthcare cost in cardiac surgery (22 minutes).
Fatalities Reported to FDA Following Blood Collection and Transfusion
Due to advances in donor screening, improved viral marker tests, automated data systems, and changes in transfusion medicine practices, the risks associated with blood transfusion continue to decrease.
Intraoperative Use of Packed Red Blood Cell Transfusion and Mortality in Patients Undergoing Abdominal or Thoracoabdominal Aortic Aneurysm Surgery
A direct association between intraoperative use of red blood cell (RBC) transfusion and perioperative mortality in patients undergoing aortic aneurysm surgery has not been studied before.
Acute Normovolemic Hemodilution is Not Beneficial in Patients Undergoing Primary Elective Valve Surgery
The objective of this study was to evaluate the effectiveness of acute normovolemic hemodilution (ANH) as a sole method of reducing allogenic blood requirement in patients undergoing primary elective valve surgery.
Prospective Comparative Study of Two Different Autotransfusion Methods Versus Control Group in Total Knee Replacement
The aim of this study was to evaluate the efficacy of two different autotransfusion methods in total knee replacement (TKR) performed without tourniquet, in comparison to allogeneic blood transfusion (ABT) only.
Red Blood Cell Hemolysis During Blood Bank Storage: Using National Quality Management Data to Answer Basic Scientific Questions
Hemolysis of red blood cells (RBCs) during blood bank storage is the most obvious manifestation of RBC storage system failure. However, its analysis is made difficult because the largest source of interunit difference is donor specific.
The Relationship Among Thromboelastography, Hemostatic Variables, and Bleeding After Cardiopulmonary Bypass Surgery in Children
We aimed to (a) compare perioperative temporal profiles of TEG(R) and laboratory hemostatic variables between patients with significant hemorrhage (BLEED) and those without (CONTROL), (b) investigate the relationship between TEG(R) variables and routine hemostatic variables, and (c) develop a model for prediction of bleeding.
Heparin Dose Response Is Independent of Perioperative Antithrombin Activity in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Low Heparin Concentrations
We hypothesized that there would be a direct association between perioperative AT activity and both heparin dose response (HDR) and heparin sensitivity index (HSI) in patients undergoing coronary artery bypass graft surgery.
Predonation of Autologous Blood Reduces Perioperative Allogenic Transfusion Requirement In Grown-up Patients With Congenital Heart Disease
To investigate the efficacy of autologous blood predonation (ABP), we focussed on a homogeneous subgroup of patients, with right ventricular outflow tract reconstruction.
Preoperative Heparin Therapy Causes Immune-Mediated Hypotension Upon Heparin Administration for Cardiac Surgery
To evaluate whether patients with positive or negative heparin antibodies who received heparin preoperatively by continuous infusion developed cardiovascular changes upon heparin administration prior to cardiopulmonary bypass.
Meta-Analysis of Clinical Studies of the Purported Deleterious Effects of “Old” (Versus “Fresh”) Red Blood Cells: Are We at Equipoise?
A meta-analysis examined whether the available data support an adequate suspicion that transfusion of old red blood cells (RBCs) is associated with increased mortality, organ failure, infection, prolonged mechanical ventilation, and prolonged stay in the hospital or the intensive care unit.
Hematocrit on Cardiopulmonary Bypass and Outcome After Coronary Surgery in Nontransfused Patients
This study aimed to identify the role of preoperative anemia and hemodilution during cardiopulmonary bypass as determinants of morbidity and mortality after coronary operations.