Thromboelastometry, Thromboelastography, and Conventional Tests to Assess Anticoagulation During Extracorporeal Support: A Prospective Observational Study
The aim of the study was to evaluate ROTEM as a tool for assessing hemostasis during ECMO, by comparing it to TEG and conventional coagulation assays.
Impact of Prothrombin Complex Concentrate and Fresh Frozen Plasma on Correction of Haemostatic Abnormalities in Bleeding Patients Undergoing Cardiac Surgery (PROPHESY Trial Results)
Our results show that 1000 IU and 1500 IU for PCC are comparable with 4 units and 5 units of FFP, respectively, in correcting coagulation abnormalities in bleeding patients undergoing cardiac surgery, and large trials are now needed to evaluate the clinical benefits and risks of both.
The Dynamics of Heparin-Binding Protein in Cardiothoracic Surgery—A Pilot Study
The usefulness of HBP for predicting postoperative infections in cardiothoracic surgery should be investigated in future studies.
Effect of Prolonged Hypothermic Cardiopulmonary Bypass, Heparin, and Protamine on Platelet: A Small-Group Study
Our findings demonstrate that protamine given after CPB plays a central role in PD and count decrease.
Coronary Artery Bypass Surgery without Blood Transfusion; Is It Possible?
Triple combination technique is safe and cost-effective in coronary artery bypass surgery. We think that most of the patients could be operated without blood transfusion with this technique.
Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis
Based on the pooled results of the available literature, RAP is associated with a significant reduction in intraoperative and whole hospital allogeneic red cell transfusion. Use of RAP may prevent hemodilution of cardiac surgical patients and thus, lessen transfusions. Additional high-quality prospective studies are necessary to determine the ideal priming volume necessary to confer the greatest benefit without incurring organ injury.
Platelet Transfusion in Cardiac Surgery: A Systematic Review and Meta-Analysis
After accounting for baseline differences, platelet transfusion was not linked with perioperative complications in cardiac surgery patients. Given the small number of observational studies, these findings should be considered hypothesis generating.
Comparison of Cell Salvage with One and Two Suction Devices During Cesarean Section in Patients With Placenta Previa and/or Accrete: A Randomized Controlled Trial
Cell salvage performed by one suction device could result in higher volume of salvaged RBCs and can be used safely for CS in patients with placenta previa and/or accrete when massive hemorrhage occurs.
Effects of Transfusion Load and Suction Pressure on Renal Function in Intraoperative Salvage Autotransfusion
After an exhaustive investigation, less than 4 units transfusion and less than 0.03 MPa suction pressure are recommended for intraoperative salvage autotransfusion.
Hematologic Evaluation of Intraoperative Autologous Blood Collection and Allogeneic Transfusion in Cardiac Surgery
Large‐volume AWB collection and reinfusion are feasible in selected cardiac surgical patients, and may be associated with prohemostatic effects according to thromboelastometry, warranting further investigation with a prospective randomized study.
Effects of Implementing Rotational Thromboelastometry in Cardiac Surgery: A Retrospective Cohort Study
The use of thromboelastometry testing was associated with increased possibility to receive coagulation product transfusions. However, it appears that thromboelastometry testing was mostly used to assist in management of major bleeding.
Cardiopulmonary Bypass-Induced Coagulopathy in Paediatric Patients: The Role of Platelets in Postoperative Bleeding. A Preliminary Study
Postoperative bleeding in children undergoing cardiac surgery with CPB was linked to younger age, longer CPB duration and significant postoperative reduction in platelet count and function. Larger studies are needed to confirm our results and define strategies to reduce postoperative bleeding in these patients.