Single-Stage Sinus Augmentation With Cancellous Iliac Bone and Anorganic Bovine Bone in the Presence of Platelet-Rich Plasma in the Miniature Pig
Aim: The aim of the present study was to evaluate the osseointegration of dental implants and bone formation in maxillary sinus grafting with autologous and anorganic bovine bone in the presence of platelet-rich plasma (PRP) in an established animal model. Material and methods: We performed bilateral maxillary sinus augmentation with 50% anorganic bovine bone and simultaneously inserted a titanium screw implant in five minature pigs. Six hundred microlitre autologous PRP were added to the left side (test). The right side (no PRP) served as control. Polychrome sequential labeling was performed. The animals were sacrificed 6 weeks after surgery. Undecalcified ground sections were evaluated by microradiography, digitized histomorphometry and under fluorescent light. Results: The mean bone implant content in the test and control group was 8.4% and 17.3% respectively (P=0.042). The mean height of newly formed mineralized bone in the augmented area of the test group was 3.6 mm and 5.7 mm respectively (P=0.342). In the PRP group, the mean area of newly formed bone in the base of the sinus was enhanced (75.23%) as compared to the control side (51.8%) (P=0.020(*)). Although PRP enhanced bone formation at the base of the maxillary sinus, it neither improved osseointegration of dental implants nor bone in-growth into the bone substitute under the selected experimental conditions.
Platelet-Rich Fibrin: Evolution of a Second-Generation Platelet Concentrate
This article describes the evolution of this novel platelet concentrate, referred to as PRF.
Promoted New Bone Formation in Maxillary Distraction Osteogenesis Using a Tissue-Engineered Osteogenic Material
Bilateral maxillary distraction was performed at a higher rate in rabbits to determine whether locally applied tissue-engineered osteogenic material (TEOM) enhances bone regeneration.
Improved Treatment of Mandibular Odontogenic Cysts With Platelet-Rich Gel
By concentrating platelets, platelet-rich plasma (PRP) with higher levels of growth factors can be obtained, which might stimulate healing processes. After platelet degranulation, massive release of growth factors and active substances occurs and gelatinous matrix-platelet-rich gel (PRG) is formed.
Effect of Different Bone Substitutes on the Concentration of Growth Factors in Platelet-rich Plasma
This study is conducted to determine the effect of different kinds of bone substitutes and collagen on the concentration of platelet-derived growth factor (PDGF) and transforming growth factor beta-1 (TGF beta-1) in platelet-rich plasma (PRP).
Use of Platelet Gel With Connective Tissue Grafts for Root Coverage: A Randomized-Controlled Trial
The aim of the present study was to compare connective tissue graft (CTG)+PRP with CTG alone in the treatment of gingival recession.
Platelet-Rich Plasma and Platelet Gel Preparation Using Plateltex(R)
Here we report the technical performance of this system in comparison with the performance of other commercially available systems: PRGF(R), PRP-Landesber, Curasan(R), PCCS(R), Harvest(R), Vivostat(R), Regen(R) and Fibrinet(R).
Platelet-Rich Plasma Enhances the Initial Mobilization of Circulation-Derived Cells for Tendon Healing
In this study, we injected platelet-rich plasma (PRP) containing various kinds of growth factors into the wounded area of the patellar tendon, and compared the effects on activation of circulation-derived cells and enhancement of tendon healing with a control group (no PRP injection).
Utility of Platelet-Rich Plasma and Growth Factors Bone in the Bone Defects
We present the results obtained with the use of platelet-rich plasma and a hydroxyapatite and bovine collagen graft in the management of bone defects.
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Periodontal Tissue Regeneration with Adipose-Derived Stem Cells
In this study, we sought to determine whether adipose-derived stem cells (ASCs) can promote periodontal tissue regeneration as well. ASCs were isolated from a Wistar rat, passaged twice, mixed with platelet-rich plasma (PRP) obtained from inbred rats, and implanted into the periodontal tissue defect that had been generated in the test rats.
Effect of Platelet-Rich Plasma on the Early Bone Formation Around Ca-P-Coated and Non-Coated Oral Implants in Cortical Bone
The purpose of the present study was to investigate the effect of local application of platelet-rich plasma (PRP) on the early healing of cortical bone around Ti implants with two different surface configurations.