Perioperative Beta‐blockers for Preventing Surgery‐related Mortality and Morbidity in Adults Undergoing Cardiac Surgery
Randomized controlled trials (RCTs) have yielded conflicting results regarding the ability of beta‐blockers to influence perioperative cardiovascular morbidity and mortality.
Porcine Mucosal Heparin Shortage Crisis! What Are the Options?
Current dramatic developments concerning heparins and related drugs have been the focus of important discussions at several regulatory, clinical, and scientific levels.
Anti-Factor Xa–Based Anticoagulation during Extracorporeal Membrane Oxygenation: Potential Problems and Possible Solutions
Choices for monitoring of unfractionated heparin (UFH) anticoagulation in extracorporeal membrane oxygenation (ECMO) patients include activated clotting time, activated partial thromboplastin time, reaction times of viscoelastic tests, and anti-factor Xa activity.
A Novel Target to Reduce Microglial Inflammation and Neuronal Damage After Deep Hypothermic Circulatory Arrest
Neuroinflammation acts as a contributor to neurologic deficits after deep hypothermic circulatory arrest.
Epinephrine-induced Electrical Storm After Aortic Surgery
Electrical storm (ES) is a potentially lethal syndrome defined as three or more sustained episodes of ventricular tachycardia or ventricular fibrillation within 24 h.
Procalcitonin to Stop Antibiotics After Cardiovascular Surgery in a Pediatric Intensive Care Unit—The PROSACAB Study
Children admitted to the pediatric intensive care unit after cardiovascular surgery usually require treatment with antibiotics due to suspicion of infection.
Cartridge-Based Thromboelastography Can Be Used to Monitor and Quantify the Activity of Unfractionated and Low-Molecular-Weight Heparins
Thromboelastography is increasingly utilized in the management of bleeding and thrombotic complications where heparin management remains a cornerstone.
Impact of Perioperative Levosimendan Administration on Risk of Bleeding After Cardiac Surgery: A Meta-analysis of Randomized Controlled Trials
Levosimendan, a calcium sensitizer and potassium channel opener, has been demonstrated to improve myocardial function without increasing oxygen consumption and to show protective effects in other organs.
Role of Bivalirudin for Anticoagulation in Adult Perioperative Cardiothoracic Practice
Bivalirudin, a direct thrombin inhibitor with a fast onset of action and short half-life, is often referred to as an alternative anticoagulant to a heparin/protamine regimen.
Haemadsorption Improves Intraoperative Haemodynamics and Metabolic Changes During Aortic Surgery with Hypothermic Circulatory Arrest
Aortic surgery involving hypothermic circulatory arrest (HCA) results in a systemic inflammatory response that may negatively influence outcome.
Antimicrobial Prophylaxis and the Prevention of Surgical Site Infection in Cardiac Surgery: an Analysis of 21 007 Patients in Switzerland
Our goal was to determine the optimal timing and choice of surgical antimicrobial prophylaxis (SAP) in patients having cardiac surgery.
Diathermy Smoke Shown to be Hazardous, So Why Are We Not Protecting Ourselves?
Diathermy smoke has been studied for over three decades and data has been collected to establish its composition.