Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding
Thrombocytopenia and platelet dysfunction induced by extracorporeal blood circulation are thought to contribute to postsurgical bleeding complications in neonates undergoing cardiac surgery with cardiopulmonary bypass (CPB).
Effect of Nitric Oxide on Postoperative Acute Kidney Injury in Patients who Underwent Cardiopulmonary Bypass: a Systematic Review and Meta-analysis with Trial Sequential Analysis
NO appeared to reduce the risk of postoperative AKI in patients undergoing CPB.
Oxygen Delivery, Oxygen Consumption and Decreased Kidney Function After Cardiopulmonary Bypass
This study could not confirm an evident correlation between O2 delivery and O2 consumption or kidney function decrease, even at values below previously specified critical levels.
St Thomas’ Hospital Polarizing Blood Cardioplegia Improves Hemodynamic Recovery in a Porcine Model of Cardiopulmonary Bypass
Polarized cardiac arrest offers similar myocardial protection and enhances functional recovery in a porcine model of cardiopulmonary bypass.
Factors Affecting Cardiovascular Physiology in Cardiothoracic Surgery: Implications for Lumped-Parameter Modeling
Cardiothoracic surgeries are complex procedures during which the patient cardiovascular physiology is constantly changing due to various factors.
International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass
Mycobacterial infection-related morbidity and mortality in patients following cardiopulmonary bypass surgery is high and and there is a growing need for a consensus-based expert opinion to provide international guidance for diagnosing, preventing and treating in these patients.
A Patient With Remote Heparin-Induced Thrombocytopenia and Antiphospholipid Syndrome Requiring Cardiopulmonary Bypass: Do Current Guidelines Apply?
Anticoagulation for cardiopulmonary bypass (CPB) is required to prevent acute disseminated intravascular coagulation and clot formation within the bypass circuit.
Review of von Willebrand Disease and Acquired von Willebrand Syndrome for Patients Undergoing Cardiac Surgery
Thus, understanding the mechanism of vWD and the treatment options available for vWD is essential for guiding the care of cardiac surgery patients.
Recovery of Cefazolin and Clindamycin in In Vitro Pediatric CPB Systems
Recovery of cefazolin was high in the neonatal and infant CPB systems and moderate in the pediatric system. We found a large discrepancy between the theoretical and measured concentrations of clindamycin in all tested CPB systems.
Mitochondrial Dysfunction in Cardiac Surgery
Mitochondria are key to cellular energy production, but are also vital to reactive oxygen species signaling, calcium hemostasis, and regulation of cell death.
Large Volume Infusions of Hydroxyethyl Starch During Cardiothoracic Surgery May Be Associated With Postoperative Kidney Injury: Propensity-Matched Analysis
Intraoperative use of HES was not associated with postoperative AKI following CPB.
Serum Levels of Interleukin-6, Interleukin-8, Interleukin-10, and Tumor Necrosis Factor-α, Renal Function Biochemical Parameters and Clinical Outcomes in Pediatric Cardiopulmonary Bypass Surgery
Higher circulatory pro-inflammatory cytokine level is associated with adverse outcomes such as increased intensive care unit stay and longer mechanical ventilation time in pediatric patients.