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Strategies to Minimize Intraoperative Blood Loss During Major Surgery
Reducing perioperative blood loss requires a multimodal and multidisciplinary approach. Although high‐quality evidence exists in certain areas, the overall evidence base for reducing intraoperative blood loss remains limited.
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Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis
Based on the pooled results of the available literature, RAP is associated with a significant reduction in intraoperative and whole hospital allogeneic red cell transfusion. Use of RAP may prevent hemodilution of cardiac surgical patients and thus, lessen transfusions. Additional high-quality prospective studies are necessary to determine the ideal priming volume necessary to confer the greatest benefit without incurring organ injury.
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The Effect of Normovolemic Modified Ultrafiltration on Inflammatory Mediators, Endotoxins, Terminal Complement Complexes and Clinical Outcome in High-Risk Cardiac Surgery Patients
The clinical benefit of normovolemic modified ultrafiltration (N-MUF) after cardiac surgery is still debated. As we have shown in a previous publication, there is a significant improvement in platelet function, so we were interested in whether ultrafiltration can reduce plasma levels of endotoxins, terminal complement complexes and cytokines after cardiopulmonary bypass (CPB) in adults with increased risk profiles.
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