Intraoperative Off-Label Reversal of Apixaban by Andexanet Alfa while on VA-ECMO Immediately After Emergent Surgery for Acute Type A Aortic Dissection
There is currently no information available on either safety issues or efficacy related to the off-label use of andexanet alfa when given after prior administration of prothrombin complex concentrate, which has been discouraged so far, and in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO).
A Case of Cytokine Hemofiltration and Extracorporeal Life Support as Treatment of Coronavirus Disease 2019 (COVID-19) Respiratory Failure
A hyperactive immune response has been implicated in COVID-19 respiratory failure. Hemofiltration with a membrane designed to remove cytokines offers a potential avenue for treatment.
Blood Transfusion Threshold in Patients Receiving Extracorporeal Membrane Oxygenation Support for Cardiac and Respiratory Failure—A Systematic Review and Meta-Analysis
The present study did not resolve uncertainty as to transfusion management in ECMO, although several studies (most of them in VV ECMO) demonstrated that a restrictive threshold has acceptable outcomes in single-center cohorts.
How I Approach Membrane Lung Dysfunction in Patients Receiving ECMO
The decision to exchange a ML is complex and without clear guidelines. In this manuscript, we outline a physiologic approach to troubleshooting this common yet high risk event.
Perfusion Cognitive Assessment Battery: Evaluating the Cognitive Performance to Improve the Practice
P-CAB represents a valuable multidisciplinary assessment tool that offers valuable information about the neurocognitive performance after the cardiac surgery.
A Last Resort When There is No Blood: Experiences and Perceptions of Intraoperative Autotransfusion Among Medical Doctors Deployed to Resource-Limited Settings
The participants found that simple IAT is under-utilised in resource-limited settings. Missed opportunities to use IAT were mainly associated with armed conflict settings and obstetrical emergencies.
Managing the Coagulopathy Associated with Cardiopulmonary Bypass.
While challenging, the effective management of CPB‐associated coagulopathy can significantly improve patient outcomes.
Mechanisms of Perioperative Brain Damage in Children with Congenital Heart Disease.
This study analyses the forms of structural and functional brain damage in the early postoperative period, along with the recent evolution of research on its contributing factors.
Elevated Procalcitonin as a Risk Factor for Postoperative Delirium in the Elderly after Cardiac Surgery—A Prospective Observational Study
In a multivariable logistic regression model, preoperative procalcitonin (odds ratio (OR) = 3.05), depressive symptoms (OR = 5.02), age (OR = 1.14), impaired daily functioning (OR = 0.76) along with CPB time (OR = 1.04) were significant predictors of postoperative delirium.
Smart Bracelet to Assess Physical Activity After Cardiac Surgery: A Prospective Study.
After cardiac surgery, wearing a smart bracelet recording daily steps is simple, well tolerated and suitable for measuring physical activity. Standard patients achieved around 6000 daily steps 2 months after discharge. 85% of this activity is reached in the first month.
Cardiopulmonary Bypass Increases Endothelial Dysfunction After Pulmonary Ischaemia-Reperfusion in An Animal Model.
CPB significantly increased the IR-mediated effects on pulmonary endothelial dysfunction. Therefore, the use of CPB during lung transplantation could be deleterious, by increasing endothelial dysfunction.
Neuroendocrine Predictors of Vasoplegia After Cardiopulmonary Bypass.
Preoperative impaired response to low-dose ACTH stimulation test is not a risk factor for post-cardiotomic vasoplegia; conversely, higher preoperative copeptin predicts the complication.