Blood Oxygenation Using Fluoropolymer-Based Artificial Lung Membranes
The blood oxygenation performance was assessed using animal sheep blood, and the fabricated fluoropolymer membranes showed competitive performance to that of commercial polyolefin membranes without any detectable hemolysis. The data also confirmed that the bottleneck in the blood oxygenation performance was not the membrane permeance but rather the rate of mass transfer in the blood phase, highlighting the importance of efficient module design.
Hyperoxia During Cardiopulmonary Bypass Is Associated With Mortality in Infants Undergoing Cardiac Surgery
Hyperoxia during cardiopulmonary bypass was an independent risk factor for mortality and may be a modifiable risk factor. Furthermore, hyperoxia during cardiopulmonary bypass was associated with four-fold greater odds of mortality within 30 days of surgery.
ECMELLA: Successful Rescue Cardiopulmonary Support in Post-Coronary Artery Bypass Graft Cardiogenic Shock with Cardiac Arrest-Case Report
Although there is limited evidence of the benefit of a combined use of mechanical support (VA-ECMO with other mechanical devices) in the management of cardiogenic shock and cardiac arrest following CABG surgery, there seems to be a lower mortality with this approach, and possibly more favourable neurological outcomes. Further research is needed to elucidate the advantages of Impella vs. intra-aortic balloon pump combined with VA-ECMO in such patients.
A New Anticoagulation Strategy Using Recombinant Human Thrombomodulin in Patients on Veno-Venous Extracorporeal Membrane Oxygenation: A Retrospective Study
In this retrospective study, we analyzed 15 patients with severe respiratory failure who were administered rhTM as an anticoagulant during VV-ECMO and found that anticoagulation therapy with rhTM is maybe a feasible option which allows for effective and safe VV-ECMO.
Concurrent Use of Renal Replacement Therapy during Extracorporeal Membrane Oxygenation Support: A Systematic Review and Meta-Analysis
RRT on ECMO was associated with higher mortality rates and a longer ICU/hospital stay compared to those without RRT. Future research should focus on minimizing renal dysfunction in ECMO patients and define the optimal timing of RRT initiation.
Perfusion Strategy Using Axillary or Femoral Cannulation for Minimally Invasive Cardiac Surgery: Experience in 270 Patients with Computed Tomography-Based Criteria
We believe our CT-based perfusion strategy using AC or FC minimized brain embolic rates. AC can be a good alternative to prevent brain embolization for minimally invasive cardiac surgery patients with advanced atherosclerotic disease.
Use of the Hypotension Prediction Index During Cardiac Surgery
HPI predicted hypotensive episodes during cardiac surgeries with a high degree of sensitivity and specificity.
Prediction of Bleeding in Pediatric Cardiac Surgery Using Clinical Characteristics and Prospective Coagulation Test Results
Prospective coagulation testing marginally improves prediction of CCB during and after cardiac surgery but the clinical impact of this is small when compared to prediction using clinical characteristics.
Perioperative Outcomes of Coronary Artery Bypass Graft Surgery in Johannesburg, South Africa
In our study, the crude perioperative mortality rate was 11.2%. Our mortality rate was significantly higher than the mortality rates reported in other developed and developing countries. To better understand the factors driving this high mortality rate, a prospective outcomes registry has been initiated, and this promises to inform on our contemporary mortality and morbidity outcomes.
Percutaneous Femoral Cannulation and Decannulation Using A Plug-Based Vascular Closure Device in Minimally Invasive Cardiac Surgery
These findings indicate that the technique of percutaneous cannulation presented in this tutorial decreases complications frequently seen with surgical cutdown. The risk of conversion to surgical cutdown iswas low. The risk of stenosis of the femoral artery seems to be reduced if distal perfusion is confirmed by ultrasound at the end of the procedure.
Hemolysis at Low Blood Flow Rates: In-Vitro and In-Silico Evaluation of A Centrifugal Blood Pump
These findings underline the urgent need for a specific pump optimized for low-flow treatment. Due to the inherent problems of available centrifugal pumps in the low-flow range, clinicians should use the current centrifugal pumps with caution, alternatively other pumping principles such as positive displacement pumps may be discussed in the future.
Risk Assessment of Acute Kidney Injury Following Cardiopulmonary Bypass
Evaluation of patients by the RIFLE versus SOP criteria yielded different results with more AKI patients detected by SOP. Based on the present data, it is concluded that patients may not prone to AKI when surgery and ischemia time will be kept short, when blood loss is mitigated to a minimum and when surgery is performed under non-hypothermic conditions.