Free Hemoglobin Ratio as a Novel Biomarker of Acute Kidney Injury After On-Pump Cardiac Surgery: Secondary Analysis of a Randomized Controlled Trial
Results from this exploratory, hypothesis-generating retrospective, observational study shows that fHb ratio at the end of CPB might be used as a novel, widely applicable biomarker for AKI. The use of fHb ratio might help for an early detection of AKI, compared with prediction based only on urinary biomarkers.
Effect of Different Types of Cerebral Perfusion for Acute Type A Aortic Dissection Undergoing Aortic Arch Procedure, Unilateral Versus Bilateral
In our study, it was observed that b-ACP procedure exhibited shorter CPB time, milder hypothermia, shorter ventilation time, lower incidence of postoperative hypoxia, and neurological dysfunction compared to u-ACP. Meanwhile, the incidence of ND was independently associated with three factors: preoperative neurological dysfunction, CPB time, and type of cerebral perfusion.
Tidal Flow Perfusion for the Artificial Placenta: A Paradigm Shift
Parameters of the tidal flow group were comparable with those of DLC. Single lumen jugular cannulation using tidal flow is a promising vascular access strategy for AP support. Successful miniaturization holds great potential for clinical translation to support extremely premature infants.
Nitric Oxide Attenuates the Inflammatory Effects of Air During Extracorporeal Circulation
The NO gas was blended into the ventilation/sweep site of the membrane lung. The platelets and leucocytes were activated by air alone. Addition of NO to the sweep gas attenuated the inflammatory response created by the air/blood interface in this model.
Impact of Prothrombin Complex Concentrate and Fresh Frozen Plasma on Correction of Haemostatic Abnormalities in Bleeding Patients Undergoing Cardiac Surgery (PROPHESY Trial Results)
Our results show that 1000 IU and 1500 IU for PCC are comparable with 4 units and 5 units of FFP, respectively, in correcting coagulation abnormalities in bleeding patients undergoing cardiac surgery, and large trials are now needed to evaluate the clinical benefits and risks of both.
Enhanced Recovery After Cardiac Surgery and Its Impact on Outcomes: A Systematic Review
ERAS in cardiac surgery has shown to be potentially safe and effective in improving certain postoperative outcomes. However, the evidence is limited by the lack of high-quality RCTs.
Gender-Based Microaggressions in Surgery: A Scoping Review of the Global Literature
While recent advancements have opened the field of surgery to women, there is still a lack of female representation, and persistent microaggressions may perpetuate this gender disparity. Addressing microaggressions against female surgeons is essential to achieving gender equity in surgical practice.
Hemadsorption
An evidence-based and personalized approach to EBPTs in sepsis is strongly advocated, in order to solve controversies in this field and optimise the management of critically ill septic patients.
Extubation during Extracorporeal Membrane Oxygenation in Adults: An International Qualitative Study on Experts’ Opinions
Highlights In all, 14 adult-ECMO experts participated in four focus groups and two interviews Seven themes were identified in this qualitative multidisciplinary […]
Esmolol in Cardiac Surgery: A Randomized Controlled Trial
In the present trial, esmolol as a cardioplegia adjuvant enhanced postoperative cardiac performance but did not reduce a composite endpoint of prolonged intensive care unit stay and/or mortality.
Changing of Haemostatic System in A Pig Model During Different Types of Hypothermic Circulatory Arrest
Moderate hypothermic circulatory arrest is more suitable for patients with coagulation dysfunction. We believe the application of deep hypothermic circulatory arrest should pay more attention to changes in coagulation rather than the anticoagulation pathway. Extrinsic coagulation factor supplementation is more effective after deep hypothermic circulatory arrest.
The Dynamics of Heparin-Binding Protein in Cardiothoracic Surgery—A Pilot Study
The usefulness of HBP for predicting postoperative infections in cardiothoracic surgery should be investigated in future studies.