Cardiac Biomarkers for Risk Stratification of Acute Kidney Injury After Pediatric Cardiac Surgery
Preoperative plasma galectin-3 and NTproBNP and the first postoperative galectin-3 and ST2 levels were independently associated with AKI in children ≥2 years old. The performance of cardiac biomarkers after cardiac surgical procedure is affected by age, and research is required to develop biomarkers for children <2 years old.
The Association Between Intraoperative Cell Salvage and Red Blood Cell Transfusion in Cardiac Surgery – An Observational Study in A Patient Blood Management Centre
Here, we evaluate the benefit of CS in a large number of patients undergoing elective cardiac surgery at a designated PBM centre. We hypothesised that the use of CS is associated with a decreased proportion of patients exposed to RBC transfusion as an individual measure in a comprehensive PBM program.
Unconscious (Implicit) Bias
Recognition, acknowledgment, and acceptance of biases in a nonjudgmental manner is key to advancing knowledge and avoiding biased behaviors.
Acute Response of Human Aortic Endothelial Cells to Loss of Pulsatility as Seen during Cardiopulmonary Bypass
These results suggest that even short-term exposure to continuous flow can potentially activate pro-inflammatory/pro-angiogenic signaling in cultured HAECs and pulsatile flow may be a successful strategy in reducing the undesirable sequalae following continuous flow CPB.
The Diagnostic Accuracy of Procalcitonin In Infectious Patients After Cardiac Surgery: A Systematic Review and Meta-Analysis
This study indicated that PCT is a promising marker for the diagnosis of sepsis for those patients who undergo cardiac surgery.
Can Peroperative Neutrophil To Lymphocyte Ratio Change (Deltanlr) Be Used as a Parameter in Predicting Acute Renal Failure Following Coronary Bypass Operations With Cardiopulmonary Bypass?
In this study, we have shown that peroperative NLR changes can be used as an effective parameter to predict ARF developing following CABG operations.
A Computational Fluid Dynamics Study of the Extracorporeal Membrane Oxygenation-Failing Heart Circulation
Using an idealized geometry of the aorta and its major branches and a peripherally inserted return cannula terminating in the iliac artery, computational fluid dynamic simulations were performed to (1) quantify perfusion as function of relative ECMO flow and (2) describe the watershed region produced by the collision of antegrade flow from the heart and retrograde ECMO flow.
Dual Veno-Arterial Extra-Corporeal Membrane Oxygenation Support in A Patient with Refractory Hyperdynamic Septic Shock: A Case Report
The commencement of a second jugulo-axillary VA ECMO secured a total blood flow of 14.3 L/min, which restored perfusion pressure and successfully bridged patient over the period of critical haemodynamic instability and ultimately may have facilitated recovery.
My Thoughts: Unspoken Truths About Gender Inequality in Surgery Across Different Cultures and Income Levels
Keywords Sexism Gender Surgeons Internship Residency
Systematic Reviews and Meta-Analyses in Cardiac Surgery: Rules of the Road – Part 1
The aim of the first part of this expert review is to discuss the limits and pitfalls of the meta-analytic approach and provide guidance on how to perform trial-level meta-analyses, with particular reference to the identification of an appropriate research question, the definition and registration of the protocol, the search strategy, the study selection, and the data abstraction.
Systematic Reviews and Meta-Analyses in Cardiac Surgery: Rules of the Road – Part 2
The aim of the second part of this expert review is to provide guidance on how to appropriately perform trial level meta-analyses, with particular focus on the quality assessment of the included studies, the choice of the appropriate statistical approach, the methods to deal with heterogeneity (including subgroup, meta-regression, and sensitivity analyses), and the appraisal of publication bias.
Cardiopulmonary Bypass Suppresses Forkhead Box O3 and Downstream Autophagy in the Diabetic Human Heart
Compared with nondiabetic patients, there was no significant upregulation of FOXO3α in diabetic patients, which could possibly explain the lack of upregulation of the autophagy process after CPB. FOXO3α could potentially serve as a therapeutic target to improve cellular homeostasis.