Neurological Complications During Veno-Venous Extracorporeal Membrane Oxygenation: Does the Configuration Matter? A Retrospective Analysis of The ELSO Database
In this large registry, the occurrence of neurological complications was not related to the type of cannulation in patients undergoing V-V ECMO.
Different Mechanisms of Oxygenator Failure and High Plasma von Willebrand Factor Antigen Influence Success and Survival of Venovenous Extracorporeal Membrane Oxygenation
vWF:Ag levels alone cannot predict early MO failure and outcome in VV ECMO patients. Probably, the mechanism of clotting disorder in combination with the vWF:Ag level seems to be essential for clot formation within the MO. In addition, vWF:Ag levels allows the identification different patient populations In particular, WGT/high vWF:Ag represented a critically ill population with higher ECMO-associated mortality.
Modern Practice and Outcomes of Reoperative Cardiac Surgery
Reoperative cardiac surgery is associated with low operative morbidity and mortality at an experienced center. Early and late CPB strategies have comparable outcomes in the context of an image-guided, team-based strategy.
Cardiac Surgery Outcome During the COVID-19 Pandemic: A Retrospective Review of the Early Experience in Nine UK Centres
To mitigate against the risks of Covid-19, particularly the post-operative burden, robust and effective pre-surgery diagnosis protocols alongside effective strategies to maintain a Covid-19 free environment are needed. Dedicated cardiac surgery hubs could be valuable in achieving safe and continual delivery of cardiac surgery.
Heparin-Free Lung Transplantation on Venovenous Extracorporeal Membrane Oxygenation Bridge
Despite the limited patient population, such an approach relies on a strong rationale and may be beneficial for managing ECMO bridging to LuTX. Prospective studies are necessary to confirm the validity of our strategy.
Prognostic Utility of KDIGO Urine Output Criteria After Cardiac Surgery
Acute kidney injury classified by KDIGO urine output criteria was not associated with other biomarkers of kidney injury or worse patient outcomes. These data suggested that KDIGO urine output criteria after cardiac surgery may overclassify AKI stage; further research is needed.
Hypercoagulopathy, Acquired Coagulation Disorders and Anticoagulation Before, During and After Extracorporeal Membrane Oxygenation in COVID-19: A Case Series
Coronavirus-induced coagulopathy and bleeding disorders during vvECMO cannot be discriminated via ‘routine’ coagulation tests. Precise and specific analyses followed by the appropriate treatment of coagulation disorders may help us develop tailored therapeutic concepts to better manage the phases described above.
Hemoadsorption Eliminates Remdesivir from the Circulation: Implications for the Treatment Of COVID-19
Remdesivir and its main active metabolite GS‐441524 are rapidly eliminated from the perfusate by the CytoSorb® adsorber device in vitro. This should be considered in patients for whom both therapies are indicated, and simultaneous application should be avoided. In general, plasma levels of therapeutic drugs should be closely monitored under concurrent CytoSorb® therapy.
Transplantation of Donor Hearts After Circulatory Death Using Normothermic Regional Perfusion and Cold Storage Preservation
Donation after circulatory death heart transplantation using thoraco-abdominal NRP and subsequent cold storage preservation for up to 129 min was safe for 4 procedures and could be a way to expand the donor heart pool while avoiding costs of machine preservation.
Hematic Antegrade Repriming: A Reproducible Method to Decrease the Cardiopulmonary Bypass Insult
Here, we describe hematic antegrade repriming as an easy and reliable method that could be applied with any circuit in the market to decrease transfusion requirements, emboli, and inflammatory responses, reducing costs and the impact of CPB on postoperative recovery.
Blood Loss Kinetics During the First 12 Hours After On-Pump Cardiac Surgical Procedures
The hourly rate of chest tube blood loss seems to be relevant to predict, within the first postoperative hours after cardiac surgical procedures, major bleeding at 12 postoperative hours. Early detection of blood loss may help to improve a patient’s blood conservation strategy because it may prompt preemptive treatments.
Cardiac Surgery in Patients With Liver Cirrhosis (CASTER) Study: Early and Long-Term Outcomes
CS outcomes in patients with LC are significantly affected in relation to the extent of preoperative liver dysfunction, but in early CTP classes, medium-term survival is acceptable. Further analysis are needed to better estimate the preoperative risk stratification of these patients.