Diabetic Pathophysiology Enhances Inflammation during Extracorporeal Membrane Oxygenation in a Rat Model
These data demonstrate that diabetes enhances proinflammatory cytokine release, renal damage, and pulmonary edema during ECMO in an animal model.
Frequency Domain Analysis and Clinical Outcomes of Pulsatile and Non-Pulsatile Blood Flow Energy During Cardiopulmonary Bypass
PP provided more energy than NP. The proportion of low frequency energy in the pulsatile or nonpulsatile flow is significantly reduced. The low-frequency energy is significantly attenuated during conduction to peripheral tissues in nonpulsatile flow. The surplus pulsatile energy influences the secretion of endothelial and inflammatory factors, and demonstrate better cerebral and kidney protective effect at the biological marker level.
Altered Fibrinolysis during and after Surgery
Major surgery induces hemostatic changes related to surgical stress, tissue destruction, and inflammatory reactions. These changes involve a shift of volume from extravascular space to intravascular and interstitial spaces, a “physiologic” hemodilution of coagulation proteins, and an increase of plasmatic fibrinogen concentration and platelets.
Albumin in Adult Cardiac Surgery: A Narrative Review
In cardiac surgical patients, albumin is widely utilized despite a lack of high- quality evidence supporting its efficacy or safety. A well-designed randomized controlled trial is needed to clarify the role of albumin in cardiac surgical patients.
Factors Associated with Delirium after Cardiac Surgery: A Prospective Cohort Study
The aforementioned risk factors are significantly and independently associated with the presentation of PD. Because some of these factors can be treated or avoided, the results of this study are highly relevant to reduce the risk of this complication and improve the care of patients undergoing cardiac surgery.
The Complex Nature of Emboli Detection During Cardiac Procedures
Certainly, as the letter authors stated, emboli source and delivery during surgical procedures is complex. Multidisciplinary teams are needed to solve this problem. We are glad that a robust body of literature precedes us and that the relatively small but extremely important research community represented by World Journal for Pediatric and Congenital Heart Surgery readers will continue to work together toward improving technology to accurately identify emboli burden and characteristics during cardiac procedures.
Does Postoperative Cognitive Decline after Coronary Bypass Affect Quality of Life?
Postoperative cognitive dysfunction and decreased QoL are common 6 months after surgery, although cognitive function and QoL were found to have improved in many patients at 6 months of follow-up. Impaired cognitive function is not associated with impaired QoL at 6 months.
A Porcine Model of Endothelial Glycocalyx Damage by Enzymatic Digestion: A Pilot Study
EG damage induced by specific enzymes was reflected by temporary changes of biochemical makers together with alteration of microcirculation and changes in fluorescent microscopy of EG layer. Our results support to further validate presented model of EG damage on a larger number of animals.
State of the Art Review: Surgical Treatment of Acute Type A Aortic Dissection
This review provides an overview of the current surgical treatment of ATAAD, focusing on new disease classifications, preoperative computed tomography angiography (CTA) assessment, new prosthesis and stent technologies, and organ-protection strategies.
Association Between the Variability of Cerebral Oxygen Saturation During Cardiopulmonary Bypass and Delayed Postoperative Neurocognitive Recovery in Cardiac Valve Surgical Patients: A Pilot Study
The real variability of rSO2 during the CPB rewarming phase was related to postoperative delayed neurocognitive recovery in patients who underwent cardiac surgery.
Protective Effect of Sevoflurane on Vascular Endothelial Glycocalyx in Patients Undergoing Heart Valve Surgery: A Randomised Controlled Trial
Sevoflurane can decrease glycocalyx degradation in patients undergoing heart valve surgery under cardiopulmonary bypass.
Preoperative Anemia and Transfusion in Cardiac Surgery: A Single-Centre Retrospective Study
Preoperative anemia is present in 15% of patients at our centre and these patients have 53% transfusion rates on surgery day. Hemoglobin concentration, eGFR, BSA, and total cardiopulmonary bypass time were predictors of transfusion on surgery day. Patients had a median of 7 days between initial visit and surgery day. Referral and anemia treatment were infrequently initiated in preoperative anemic patient.