Increased Glucose Variability Is Associated With Major Adverse Events After Coronary Artery Bypass
Increased 24-hour but not 12-hour postoperative GV after CABG is a predictor of poor outcomes. Preoperative HbA1c is not associated with MAEs after adjusting for postoperative mean glucose and GV.
Microcirculation Evolution in Patients on Venoarterial Extracorporeal Membrane Oxygenation for Refractory Cardiogenic Shock
Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation.
Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery The FIBRES Randomized Clinical Trial
In patients undergoing cardiac surgery who develop clinically significant bleeding and hypofibrinogenemia after cardiopulmonary bypass, fibrinogen concentrate is noninferior to cryoprecipitate with regard to number of blood components transfused in a 24-hour period post bypass.
Early and Long-Term Outcomes Comparing Neonates, Infants, and Preadolescents Requiring Extracorporeal Membrane Oxygenation for Heart Failure
Veno-arterial extracorporeal membrane oxygenation is a lifesaving therapeutic chance for pediatric patients in the setting of either failure to wean from cardiopulmonary bypass or failed resuscitation from cardiac arrest.
Coronary Artery Bypass Confers Intermediate-Term Survival Benefit over Percutaneous Coronary Intervention with New-Generation Stents in Real-World Patients with Multivessel Coronary Artery Disease, Including Left Main Disease: A Retrospective Analysis of 6383 Patients
In this contemporary cohort of real-world patients with MVD, CABG was associated with increased intermediate-term survival compared to PCI with new-generation drug-eluting stents.
Antegrade Selective Cerebral Perfusion Reduced In-hospital Mortality and Permanent Focal Neurological Deficit in Patients with Elective Aortic Arch Surgery
Elective aortic arch surgery is associated with acceptable early and late outcomes. The ASCP is associated with a significant reduction in-hospital mortality and occurrence of permanent neurological deficits.
Miscategorization of Deaths in the US Food and Drug Administration Adverse Events Database
As the US Food and Drug Administration (FDA) moves to hasten approval of medical devices, data from postmarketing studies and registries are increasingly relied on to inform decision-making.
Epidemiology of Acute Kidney Injury Among Paediatric Patients After Repair of Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery
Acute kidney injury (AKI) is a prevalent complication after the surgical repair of paediatric cardiac defects and is associated with poor outcomes.
Novel Use of Cangrelor with Heparin During Cardiopulmonary Bypass in Patients with Heparin-induced Thrombocytopenia who Require Cardiovascular Surgery: A Case Series
Optimal anticoagulation strategy during cardiopulmonary bypass (CPB) remains uncertain in patients with heparin-induced thrombocytopenia (HIT) who require urgent/emergent cardiac surgery.
Peak Creatinine, Cardiopulmonary Bypass and Mortality After Stage One Single-ventricle Reconstruction
It is important to identify therapies which minimise complications associated with prolonged cardiopulmonary bypass duration in high risk populations.
Protamine
Protamine is an FDA-approved drug for use in neutralizing the effect of unfractionated heparin.
Comparison of the Efficacy of Transthoracic Cannulation into the Ascending Aorta Versus Femoral Artery Cannulation in Minimally Invasive Cardiac Surgery
Transthoracic cannulation into the ascending aorta is reliable and can be safely performed.