Biomarker-Guided Implementation of the KDIGO Guidelines to Reduce the Occurrence of Acute Kidney Injury in Patients after Cardiac Surgery (PrevAKI-multicentre): Protocol for a Multicentre, Observational Study Followed by Randomised Controlled Feasibility Trial
The purpose of the observational survey is to explore the adherence to the KDIGO recommendations in routine clinical practice. The second phase is a randomised controlled trial. The objective is to investigate whether the trial protocol is implementable in a large multicentre, multinational setting.
Preconditioning Strategies to Prevent Acute Kidney Injury
In this review, the most attractive strategies and the current mechanistic concepts are introduced and discussed. Furthermore, we present clinical trials evaluating the feasibility of preconditioning in the clinical setting.
Long‐Term Survival and Cognitive Function According to Blood Pressure Management During Cardiac Surgery. A Follow‐up
No difference in mortality nor in the level of cognitive functioning was found according to blood pressure target during cardiac surgery long‐term at 3‐year follow‐up.
Bioelectrical Impedance Analysis for Monitoring Fluid and Body Cell Mass Changes in Patients Undergoing Cardiopulmonary Bypass
Changes in body fluids during and after cardiopulmonary bypass are inevitable. The increase in total body weight shows that this fluid load shifts to the extracellular space during bypass and the fluid load in this area passes into the intravascular area in the early postoperative period.
Are Standard Follow-Up Parameters Sufficient to Protect Neurocognitive Functions in Patients with Diabetes Mellitus who Underwent Coronary Artery Bypass Grafting?
In patients followed up with standard parameters, a significant decrease in cognitive function was observed in the early period. However, the use of advanced neuromonitoring methods can significantly prevent this decrease in cognitive functions.
To Purge or Not to Purge
Based on these results, purging while confronted with continuous GME challenge did not result in an increased filter efficiency.
Hail and Farewell
On December 30, 2019, Aaron Grant Hill, a leader whose contributions shaped the development of the field of cardiovascular perfusion, passed away surrounded by his family and friends after a long illness.
Platelet Mapping by Thromboelastography and Whole Blood Aggregometry in Adult Patients Supported by Mechanical Circulatory Support Device on Aspirin Therapy
When used with proper guidelines for interpretation, specifically when MAActivator ≤ 40 mm, TPM is a suitable and reliable test to use for MCS patients on aspirin.
Deep Hypothermic Circulatory Arrest Activates Neural Precursor Cells in Neonatal Brain
Neonatal piglet ACP at 18°C or 25°C provides adequate protection from increased brain cellular apoptosis. In contrast to ACP however, DHCA induces brain Nestin expression, indicating activation of neural progenitor cells and the potential of altering neonatal neurodevelopmental progression.
Neck Cannulation for Bypass in Redo Sternotomy in Children and Adults with Congenital Heart Disease
Cannulation of the right neck vessels for peripheral cardiopulmonary bypass prior to high-risk redo sternotomy in children and adults with congenital heart disease is a safe and effective strategy.
Assessing Efficacy of CytoSorb Haemoadsorber for Prevention of Organ Dysfunction in Cardiac Surgery Patients with Infective Endocarditis: REMOVE-Protocol for Randomised Controlled Trial
The REMOVE study is an interventional randomised controlled multicenter trial with a group sequential (Pocock) design for assessing efficacy of CytoSorb in patients undergoing cardiac surgery for IE.
Pulsatile Versus Nonpulsatile Flow During Cardiopulmonary Bypass Extent of Hemolysis and Clinical Significance
We conclude that pulsatile CPB using roller pumps results in a greater extent of hemolysis. The clinical significance, however, is not yet known.