Is Aortic Valve Replacement with a Minimally Invasive Extracorporeal Circuit a Contemporary Option for Octogenarians?
SAVR utilizing a minimally invasive extracorporeal circuit improves the quality of patient care and can offer an alternative to TAVR in octogenarians.
Closed-Loop Control of Vasopressor Administration in Patients Undergoing Cardiac Revascularization Surgery
The authors of the present article developed an automated closed-loop vasopressor (CLV) controller to improve the titration of vasopressor (eg, norepinephrine) in order to maintain MAP within a narrow range (§5 mmHg of the chosen target) in the perioperative setting.
Acute Kidney Injury after Congenital Heart Disease Surgery: A Single-Center Experience in a Low- to Middle-Income Country
Most patients with AKI showed spontaneous resolution. Prolonged CPB time and increased hemoglobin were found to be significant risk factors.
Pitfalls of Retrograde Cardioplegia Cannulation: Left Atrium Dissection
Left atrial dissection (LAD) is a rare complication of cardiac surgery. We present a case of LAD that occurred during a partial arch repair for Stanford acute type A aortic dissection.
Intra-aortic Balloon Counterpulsation Timing: A New Numerical Model for Programming and Training in the Clinical Environment
The new IABP module is easy to manage and can be used as a training tool in a clinical setting. Although based on literature data, the outcome of the simulations is encouraging. Additional work is ongoing with a view to further validate its features.
Haemoglobin Oxygen Affinity in Patients with Severe COVID‐19 Infection
We have measured Hb O2 affinity curves from severely ill COVID‐19 patients and, in comparison to age‐ and sex‐matched controls, find no evidence for a shift in O2 affinity that would support any change in clinical management.
Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research
It is our hope that the present document will encourage and stimulate future prospective studies and randomized trials to study the safety, efficacy, and optimal use of these agents for prevention or management of thrombosis in COVID-19.
Charting a Safe and Expeditious Course Back to Elective Cardiac Surgery During the COVID-19 Pandemic
What has become clear amidst the flux and uncertainty of the pandemic is that we must find a way to remain available to our patients by charting a safe and expeditious path toward resumption of elective cardiac surgery.
Towards Integrative Neuromonitoring of the Surgical Newborn – A Systematic Review
Neuromonitoring with the techniques currently used will neither help our understanding of the altered neonatal pathophysiology, nor enable early detection of deviation from the norm. The modalities lack specificity and are not related to clinical (long-term) outcome or prognosis. Accordingly, we were unable to draw up a monitoring guideline.
Engineering Blood Outgrowth Endothelial Cells to Optimize Endothelial Nitric Oxide Synthase and Extracellular Matrix Production for Coating of Blood Contacting Surfaces
Taken together, our findings demonstrate that cell-ECM interactions are fundamental to the regulation of eNOS in BOECs and suggest that disruption of key intracellular pathways (such as ROCK) may be necessary to enhance functional activity of an endothelialized surface.
Volatile Anesthesia Versus Total Intravenous Anesthesia During Cardiopulmonary Bypass: A Narrative Review on the Technical Challenges and Considerations
With no demonstrable benefit of volatile anesthetics over TIVA for CABG, this narrative review focuses on the technical challenges and considerations regarding the administration of volatile anesthesia versus TIVA during CPB.
Review and Reflections about Pulsatile Ventricular Assist Devices from History to Future: Concerning Safety and Low Haemolysis — Still Needed
Volume displacement pumps can produce high blood pressure, so they are indispensable for clinical use today and in the future. In this work, nearly all pulsatile blood pumps used in clinical life are described.