ECCO2R Therapy in the ICU: Consensus of A European Round Table Meeting
Insights from this group of experienced physicians suggest that ECCO2R therapy may be an effective supportive treatment for adults with ARDS or ae-COPD. Further evidence from randomised clinical trials and/or high-quality prospective studies is needed to better guide decision making.
Sickle Cell-Related Complications in Patients Undergoing Cardiopulmonary Bypass
In this cohort of patients, older age, longer CPB times, lower median temperature, and the utilization of deep hypothermic circulatory arrest appear to play an important role in the development of complications.
Extracorporeal Blood Purification Treatment Options For COVID-19: The Role of Immunoadsorption
Several extracorporeal blood purification therapies are now available, and most of them target endotoxins and/or the cytokines and aim improving the immune response. For this purpose, plasmapheresis and immunoadsorption may be an important adjunctive treatment option to manage the complications caused by cytokine storm in critically ill patients with COVID-19.
Thromboelastography Profiles of Critically Ill Patients With Coronavirus Disease 2019
A large proportion of critically ill patients with coronavirus disease 2019 have hypercoagulable thromboelastography profiles with additional derangements related to fibrinogen and platelet function. As the majority of patients have an elevated thromboelastography maximum amplitude, a follow-up study evaluating platelet aggregation would be instructive.
A Pharmacokinetic and Pharmacodynamic Investigation of an ε-Aminocaproic Acid Regimen Designed for Cardiac Surgery with Cardiopulmonary Bypass
This regimen provided maximum EACA concentrations near the time of protamine administration, with a total perioperative dose of 15 g.
Blood Management in A Patient with Anti-Oka Antibody Who Underwent Cardiac Surgery Using Cardiopulmonary Bypass: A Case Report
Multidisciplinary intraoperative blood management in a patient with anti-Oka antibody facilitated successful cardiac surgery using CPB, along with effective use of limited blood products.
Efficacy of Glyceryl Trinitrate (GTN) To Facilitate the Rewarming Process During Cardiopulmonary Bypass
Higher dose GTN infusion during rewarming on CPB does not improve peripheral-core temperature gradient post operatively and has no effect on post-operative lactate concentrations.
Effect of Antithrombin in Fresh Frozen Plasma on Hemostasis After Cardiopulmonary Bypass Surgery
Fresh frozen plasma administration increased antithrombin activity and caused activated clotting time prolongation, but then increased clotting ability. Thus, testing by rotational thromboelastometry after cardiopulmonary bypass could be valuable in the detection of comprehensive clotting ability.
Conventional Versus Minimally Invasive Extracorporeal Circulation In Patients Undergoing Cardiac Surgery: Protocol For A Randomised Controlled Trial (COMICS)
The trial is feasible but criteria for progressing to a full trial were not met on time. The Trial Steering and Data Monitoring Committees have recommended that the trial should currently continue.
Continuous Cerebral and Myocardial Selective Perfusion in Neonatal Aortic Arch Surgery
CCMSP is a safe and reproducible strategy for cerebral, myocardial and visceral protection in neonatal aortic arch repair, with or without VSD closure, resulting in low complication and mortality.
Effects Of Pulmonary Perfusion During Cardiopulmonary Bypass On Lung Functions After Cardiac Operation
Pulmonary artery perfusion during aortic cross‐clamping provides better oxygenation and preservation of the wall alveolar integrity after coronary artery bypass grafting surgery.