The Relationships of Cerebral and Somatic Oxygen Saturation with Physiological Parameters in Pediatric Cardiac Surgery with Cardiopulmonary Bypass: Analysis Using the Random-Effects Model.
Through the whole surgical period, ScO2 correlated strongly with mean blood pressure regardless of the physiological type. the physiological parameters affecting ScO2 and SrO2 were rather different. Accordingly, the significance of monitoring of cerebral and somatic tissue oxygen saturation in pediatric cardiac surgery should be further evaluated.
Impact of Haemolysis On Vancomycin Disposition in A Full-Term Neonate Treated with Extracorporeal Membrane Oxygenation.
Vancomycin elimination may be severely prolonged due to ECMO-induced haemolysis and acute kidney injury, while hypothesis of direct increase of vancomycin levels by releasing the drug from blood cells during haemolysis has been disproved.
Population Pharmacokinetics of Cefazolin Before, During and After Cardiopulmonary Bypass in Adult Patients Undergoing Cardiac Surgery.
PPK modelling with simulation may be valuable for devising a cefazolin prophylaxis protocol for patients undergoing cardiac surgery with CPB.
A Retrospective Analysis of CO2 Derived Goal-Directed Perfusion Variables Under Normothermic Conditions: Do We Need to Re-Evaluate Threshold Values?
Because CO2 production during bypass depends on patient temperature, a different cutoff value, that may take into account the influence of demographic variables, should be determined during normothermic CPB.
No Bad Blood — Surviving Severe Anemia Without Transfusion
Physicians who accept the challenges of learning how to treat patients safely and successfully without the traditional safety net of blood transfusion may experience a new level of confidence and expanded opportunities for providing quality care for all patients.
Characteristics of Pediatric Extracorporeal Membrane Oxygenation Programs in the United States and Canada
The majority of pediatric ECMO centers have adopted the infrastructure recommendations from the Extracorporeal Life Support Organization. However, there remains broad variability of practice characteristics and organizational infrastructure for pediatric ECMO centers across the United States and Canada.
Protocol-Driven Daily Optimisation of Venovenous Extracorporeal Membrane Oxygenation Blood Flows: An Alternate Paradigm?
This staged approach to weaning VV ECMO allows us to fully utilise the “decoupling” of oxygenation and decarboxylation that is possible only during extracorporeal support.
A Novel Escalation from Veno-Venous Bypass to Veno-Venous ECMO During Orthotopic Liver Transplantation. A Case Report
this is the first documented case that extracorporeal CO2 removal (ECCO2R) is used to optimize the biochemistry profile intraoperatively during a LT.
Incidental Cannulation of Left Ventricular Thebesian Vein
The catheter moved during the procedure, inadvertently cannulating a Thebesian vein with contrast injection.
Mechanical Circulatory Support to Treat Pulmonary Embolism: Venoarterial Extracorporeal Membrane Oxygenation and Right Ventricular Assist Devices
For patients with massive pulmonary embolism who are not candidates for conventional interventions or whose conditions are refractory, mechanical circulatory support in the form of RVAD placement or ECMO may be considered. Larger comparative studies are needed.
Preoperative COVID-19 Testing for Cardiovascular Procedures in Endemic Areas Should be Mandatory
It is extremely important for patients, healthcare providers, and the community at large to aggressively test for COVID-19 in the preprocedural period when the infection is endemic.
COVID-19 and ECMO: An Unhappy Marriage of Endothelial Dysfunction and Hemostatic Derangements
It is the authors’ perspective that it is through the integration of diagnostic assessment of viscoelastic testing with dedicated management schemes, up to and including the titration of antifibrinolytic therapies, that unmasks the capacity of this technology to enhance clinical outcomes.