Safely Repositioning Dual-Lumen ECMO Cannulas with A Transfemoral Lasso Snare
We describe three patients who successfully had dual-lumen cannulas repositioned without cessation of ECMO using a transfemoral “lasso” technique.
Comparison of A Perfusion Simulator to A Clinical Operating Room: Evaluation of Eye Tracking Data and Subjective Perception. A Pilot Study
The use of the simulator for (advanced) training is accepted and explicitly requested by perfusionists. Yet further research is needed to identify the decisive factors (like simulation duration or additional tasks) for a valid execution in the simulator. Furthermore, a larger sample size should be regarded to allow statistical analysis.
Brain Protection in Aortic Arch Surgery: An Evolving Field
The neurologic outcomes of brain protection in aortic arch surgery largely depend on the following three major components: cerebral temperature, circulatory arrest time, and cerebral perfusion during circulatory arrest.
Hype or Hope: Vagus Nerve Stimulation Against Acute Myocardial Ischemia-Reperfusion Injury
In this review, we describe the protective role of VNS in myocardial I/R injury and related potential mechanisms. Then, we discuss the challenge and the opportunity of VNS in the treatment of acute myocardial I/R injury.
Validation of a Novel NeurOs Cerebral Oximetry Monitor Against the INVOS Monitor During Cardiac Surgery
In conclusion, the novel NeurOs system was found to correlate with INVOS cerebral oximetry measurements during cardiac surgery.
Associations Between Mean Arterial Pressure During Cardiopulmonary Bypass and Biomarkers of Cerebral Injury in Patients Undergoing Cardiac Surgery: Secondary Results from A Randomized Controlled Trial
We found no significant differences in levels of biomarkers of neurological injury in patients undergoing elective or subacute CABG and/or aortic valve replacement randomized to either a target MAP of 40–50 mmHg or a target MAP of 70–80 mmHg during CBP.
Role of Extracorporeal Membrane Oxygenation in Critically Ill COVID-19 Patients and Predictors of Mortality
The present study suggests that ECMO is a potentially lifesaving treatment for selected critically ill COVID‐19 patients. Considering IL‐6 and NT‐per‐BNP, in addition to the RESP score, may enhance outcome predictions.
Influence of Blood Haemoglobin Concentration on Renal Haemodynamics and Oxygenation During Experimental Cardiopulmonary Bypass in Sheep
In experimental CPB blood transfusion to increase Hb concentration from ~7 g dL−1 to ~9 g dL−1 did not improve renal cortical or medullary tissue PO2 even though it decreased whole kidney oxygen extraction.
The Effect of Vacuum-Assisted Venous Drainage on Hemolysis During Cardiopulmonary Bypass
There was no significant increase in hemolysis among the groups, which demonstrates that the VAVD technique, even if lower negative pressure is preferred, can be applied safely and effectively to improve venous drainage and consequently, cardiac decompression, even if smaller venous cannulas are used, and also avoid from superfluous fluid addition to sustain adequate extracorporeal perfusion.
Continuous Ultrafiltration During Extracorporeal Circulation and Its Effect on Lactatemia: A Randomized Controlled Trial
The use and control of continuous high-volume hemofiltration through a polyethersulfone membrane during heart-lung surgery could potencially prevent postoperative complications. The reduction of lactatemia implied a reduction in intubation time, a decrease in morbidity and mortality in the intensive care unit and a shorter hospital stay.The use and control of continuous high-volume hemofiltration through a polyethersulfone membrane during heart-lung surgery could potencially prevent postoperative complications. The reduction of lactatemia implied a reduction in intubation time, a decrease in morbidity and mortality in the intensive care unit and a shorter hospital stay.
Shear Stress Associated with Cardiopulmonary Bypass Induces Expression of Inflammatory Cytokines and Necroptosis In Monocytes
Our study identifies a shear-stress modulated molecular mechanism that drives systemic inflammation in pediatric CPB patients. These are also the first data to demonstrate that shear-stress causes necroptosis. Finally, we observe that calcium and TNFα signaling are novel targets to ameliorate post-CPB inflammation.
Newly Developed Pediatric Membrane Oxygenator that Suppresses Excessive Pressure Drop in Cardiopulmonary Bypass and Extracorporeal Membrane Oxygenation (ECMO)
This article developes a pediatric membrane oxygenator that is compact, high performance, and highly safe.