Retrograde Autologous Priming of the Cardiopulmonary Bypass Circuit: Safety and Impact on Postoperative Outcomes
The aim of this investigation was to examine the safety of RAP and to determine the effect of RAP on adverse outcomes after cardiac surgery.
Autologous Platelet Concentrate and Vacuum-Assisted Closure Device Use in a Nonhealing Total Knee Replacement
Following a total knee replacement surgery, a 51-yearold insulin-dependent patient presented with complications of impaired healing and postoperative trauma to the wound site.
Heparin-Coated Adult ECMO vs. Ventricular Assist Devices: A Decision Analysis Modeling Approach
This model suggests that patients should be supported on heparincoated ECMO for 2–3 days to evaluate their potential for recovery before instituting more expensive ventricular assist devices.
In Vivo Comparison Study of FDA-Approved Surface-Modifying Additives and Poly-2-Methoxyethylacrylate Circuit Surfaces Coatings During Cardiopulmonary Bypass
The purpose of this double-blind prospective and randomized study was to examine the effects of surface-modifying additives (SMAs) and poly-2-methoxyethylacrylate (PMEA) circuits on platelet count, platelet function (Sonoclot), postoperative chest tube drainage volume, peri- and postoperative blood product use, extubation time, and intensive care time.
Correlation of Perioperative Platelet Function and Coagulation Tests With Bleeding After Cardiopulmonary Bypass Surgery
The authors evaluated the correlation of post-cardiopulmonary bypass surgery bleeding, measured as 24-hour chest tube output/kilogram body weight, with platelet function tests using glass bead adhesion and Thrombelastograph Platelet Mapping.
Pump-Induced Platelet Aggregation With Subsequent Hypotension: Its Mechanism and Prevention With Clopidogrel
The present study investigates the mechanism of pump-induced platelet aggregation and its possible prevention.
Magnesium as a Neuroprotectant in Cardiac Surgery: A Randomized Clinical Trial
We sought to evaluate magnesium as a neuroprotectant in patients undergoing cardiac surgery with cardiopulmonary bypass.
Evaluation of Biocompatible Cardiopulmonary Bypass Circuit Use During Pediatric Open Heart Surgery
The contact of blood with nonbiological surfaces during cardiopulmonary bypass (CPB) induces a whole body inflammatory response and increases postoperative morbidity directly related to bleeding complications and end organ dysfunction.
Whole Blood Cardioplegia (Minicardioplegia) Reduces Myocardial Edema After Ischemic Injury and Cardiopulmonary Bypass
While blood:crystalloid cardioplegia is the clinical standard for patients undergoing cardiopulmonary bypass (CPB), it has been postulated that whole blood minicardioplegia may benefit the severely injured heart by reducing cardioplegic volume, thereby reducing myocardial edema.
Is Hypothermia a Benefit? Von Willebrand Factor in Pediatric Cardiopulmonary Bypass
Our objective was to find a correlation between CPB and plasma levels of vWf in pediatric patients operated on for congenital heart defects.
The In vitro Effect of Different PRP Concentrations on Osteoblasts and Fibroblasts
The aim of this study was to assess the biological rationale for the use of platelet-rich plasma (PRP) by evaluating the effect of different concentrations of PRP on osteoblasts (OB) and fibroblasts (FB) function in vitro.
Platelets Accelerate Gastric Ulcer Healing Through Presentation of Vascular Endothelial Growth Factor
In this study, we examined the effects of orally administered human platelets on the healing of gastric ulcers in rats, and determined the contribution of VEGF and endostatin to healing in this model.