The Cardiotomy Trial: A Randomized, Double-Blind Study to Assess the Effect of Processing of Shed Blood During Cardiopulmonary Bypass on Transfusion and Neurocognitive Function
We sought to evaluate the effects of cardiotomy blood processing on blood product use and neurocognitive functioning after cardiac surgery.
Evolution of Adverse Changes in Stored RBCs
We analyzed changes occurring during RBC storage focusing on RBC deformability, RBC-dependent vasoregulatory function, and S-nitrosohemoglobin (SNO-Hb), through which hemoglobin (Hb) O2 desaturation is coupled to regional increases in blood flow in vivo (hypoxic vasodilation).
The Anatomy of Human Platelets
Platelets are the smallest corpuscular components of human blood (diameter 2-4µm) - the physiological number varies from 150.000 to 300.000/mm³ blood.
The Importance of Surgical Coagulation (Video)
This video highlights the coagulation pathways and the importance of surgical coagulation.
Association of RBC Transfusion With Mortality in Patients with Acute Lung Injury
We assessed the effect of RBC transfusion on in-hospital mortality in patients with acute lung injury (ALI).
Influence of Platelet-Rich Plasma on Bone Regeneration: A Histomorphometric Study in Rabbit Calvaria
The aim of this study was to evaluate whether local application of platelet-rich plasma (PRP) would induce bone regeneration in cranial defects on rabbits.
Alveolar Ridge Preservation Prior to Implant Placement With Surgical-Grade Calcium Sulfate and Platelet-Rich plasma: A Pilot Study in a Canine Model
To evaluate the combination of surgical-grade calcium sulfate (SGCS) and platelet-rich plasma (PRP) for alveolar ridge preservation prior to implant placement.
Inhibition of Neutrophil Activity Improves Cardiac Function After Cardiopulmonary Bypass
The arterial in line application of the leukocyte inhibition module (LIM) in the cardiopulmonary bypass (CPB) limits overshooting leukocyte activity during cardiac surgery.
Continuous-Flow Cell Saver Reduces Cognitive Decline in Elderly Patients After Coronary Bypass Surgery
Processing of shed blood with cell saver before transfusion may limit cerebral microembolization and reduce cognitive decline after surgery.
Heparin, Protamine, Aminocaproic Acid, and Aprotinin: Old Problems, New Data
Dr. John Butterworth discussed problems and concerns associated with the use of heparin, protamine, Amicar, and aprotinin in cardiac surgery.
Healthcare Heroes Heart-to-Heart Mission (Video)
John Biffar documents Dr. Pascotto's Heart-to-Heart cardiac surgey mission in the Dominican Republic.