Impact of Prothrombin Complex Concentrate and Fresh Frozen Plasma on Correction of Haemostatic Abnormalities in Bleeding Patients Undergoing Cardiac Surgery (PROPHESY Trial Results)
Our results show that 1000 IU and 1500 IU for PCC are comparable with 4 units and 5 units of FFP, respectively, in correcting coagulation abnormalities in bleeding patients undergoing cardiac surgery, and large trials are now needed to evaluate the clinical benefits and risks of both.
Enhanced Recovery After Cardiac Surgery and Its Impact on Outcomes: A Systematic Review
ERAS in cardiac surgery has shown to be potentially safe and effective in improving certain postoperative outcomes. However, the evidence is limited by the lack of high-quality RCTs.
Gender-Based Microaggressions in Surgery: A Scoping Review of the Global Literature
While recent advancements have opened the field of surgery to women, there is still a lack of female representation, and persistent microaggressions may perpetuate this gender disparity. Addressing microaggressions against female surgeons is essential to achieving gender equity in surgical practice.
Hemadsorption
An evidence-based and personalized approach to EBPTs in sepsis is strongly advocated, in order to solve controversies in this field and optimise the management of critically ill septic patients.
Extubation during Extracorporeal Membrane Oxygenation in Adults: An International Qualitative Study on Experts’ Opinions
Highlights In all, 14 adult-ECMO experts participated in four focus groups and two interviews Seven themes were identified in this qualitative multidisciplinary […]
Esmolol in Cardiac Surgery: A Randomized Controlled Trial
In the present trial, esmolol as a cardioplegia adjuvant enhanced postoperative cardiac performance but did not reduce a composite endpoint of prolonged intensive care unit stay and/or mortality.
Changing of Haemostatic System in A Pig Model During Different Types of Hypothermic Circulatory Arrest
Moderate hypothermic circulatory arrest is more suitable for patients with coagulation dysfunction. We believe the application of deep hypothermic circulatory arrest should pay more attention to changes in coagulation rather than the anticoagulation pathway. Extrinsic coagulation factor supplementation is more effective after deep hypothermic circulatory arrest.
The Dynamics of Heparin-Binding Protein in Cardiothoracic Surgery—A Pilot Study
The usefulness of HBP for predicting postoperative infections in cardiothoracic surgery should be investigated in future studies.
Effect of Prolonged Hypothermic Cardiopulmonary Bypass, Heparin, and Protamine on Platelet: A Small-Group Study
Our findings demonstrate that protamine given after CPB plays a central role in PD and count decrease.
Feeding Intolerance and Risk of Poor Outcome in Patients Undergoing Cardiopulmonary Bypass Surgery
Thus, the incidence of FI within seven days of EN after CPB was high, which was associated with a poor prognosis.
Outcomes after Intra-Aortic Balloon Pump Insertion in Cardiac Surgery Patients
Preoperative insertion of an intra-aortic balloon pump was not associated with a lower 30-day mortality or reduced length of postoperative hospital stay compared to intraoperative insertion.