In Vivo Lamellar Keratoplasty Using Platelet-Rich Plasma as a Bioadhesive
The use of standard sutures has been replaced by platelet-rich plasma (PRP), a bioadhesive agent, in several surgical procedures. This prompted us to test PRP efficacy in experimental lamellar keratoplasty.
Platelet Hyperreactivity in Response to On- and Off-pump Coronary Artery Bypass Grafting
The aim of this study was to evaluate the changes in platelet reactivity in response to cardiac surgery, both OPCAB and CABG.
Increased Accuracy in Heparin and Protamine Administration Decreases Bleeding: A Pilot Study
The purpose of the study was to evaluate whether a heparin–protamine titration system, Hemochron RxDx, could reduce postoperative bleeding and blood transfusion.
Can Pulsatile Cardiopulmonary Bypass Prevent Perioperative Renal Dysfunction during Myocardial Revascularization in Elderly Patients?
Since older subjects have a higher risk of acute renal failure, we have extended our study to evaluate the specific impact of pulsatile CPB on the perioperative renal function in elderly patients.
Use of Autologous Platelet-rich Plasma to Treat Muscle Strain Injuries
Standard nonoperative therapy for acute muscle strains usually involves short-term rest, ice, and nonsteroidal anti-inflammatory medications, but there is no clear consensus on how to accelerate recovery.
Effects of Haemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
The aim of our present study was to evaluate the ability of antioxidant therapy with mannitol or haemofiltration during CPB to modulate this immunosuppression after CPB.
An 11-Year, Single-institution Analysis of Intra-aortic Balloon Pump Use in Cardiac Surgery
The primary objective of this study was to analyze perioperative intra-aortic balloon pump (IABP) insertion in patients undergoing cardiac surgery in the authors' institution from 1995 to 2005 and to propose an explanation for changes in use over this period.
Single Center Experience With a Low Volume Priming Cardiopulmonary Bypass Circuit for Preventing Blood Transfusion in Infants and Small Children
This retrospective study analyzed the current practice of blood transfusion-free open-heart surgery in 536 children weighing 5-20 kg undergoing surgery between 2004 and 2007.
Tranexamic Acid and Aprotinin in Low and Intermediate-Risk Cardiac Surgery: A Non-Sponsored, Double-Blind, Randomised, Placebo-Controlled Trial
We wanted to compare the effectiveness of tranexamic acid versus aprotinin in reducing postoperative blood loss and transfusion requirements in the patient group representing the majority of cardiac surgery patients: low- and intermediate-risk patients.
Transfusion-Related Acute Lung Injury: Current Concepts for the Clinician
Much more research is needed to understand the blood component and patient risk factors for TRALI so that novel strategies for treatment and additional measures to reduce the risk of TRALI can be developed.
Thrombelastography
In the past decades there has been an increasing interest for TEG in clinical practice. In this paper we present the rationale for the method and a discussion of the possible application of TEG.
Integrated Model of Endothelial NO Regulation and Systemic Circulation for the Comparison Between Pulsatile and Continuous Perfusion
Many experimental studies concerning nitric oxide (NO) release from endothelium and its vasodilative action are available in the literature, but no analytical description or modeling of these phenomena can be found.