Hemostatic Resuscitation for Massive Bleeding: The Paradigm of Plasma and Platelets – A Review of the Current Literature
Continued hemorrhage remains a major contributor of mortality in massively transfused patients and controversy regarding the optimal management exists. Recent studies indicate a possible survival benefit in patients receiving a higher ratio of plasma and platelets (PLTs) to red blood cells (RBCs) than what is recommended in current transfusion guidelines.
Acute Transfusion-Associated Lung Injury (TRALI): The Obvious and the Incomprehensible
Acute transfusion-associated lung injury (TRALI) is an acute lung injury associated with and develops within 6 hours after the transfusion of components and blood preparations.
Plasmapheresis and Heparin Reexposure as a Management Strategy for Cardiac Surgical Patients with Heparin-Induced Thrombocytopenia
Heparin-induced thrombocytopenia (HIT) complicates the management of patients presenting for cardiac surgery, because high-dose heparin anticoagulation for cardiopulmonary bypass is contraindicated in these patients.
Does Point of Care Prothrombin Time Measurement Reduce the Transfusion of Fresh Frozen Plasma in Patients Undergoing Major Surgery? The POC-OP Randomized-Controlled Trial
Point of care testing of prothrombin time ensures that one major parameter of coagulation is available in the operation theatre within minutes. It is fast, easy to perform, inexpensive and may enable physicians to rationally determine the need for FFP.
Early Induction of Hypothermia During Cardiac Arrest Improves Neurological Outcomes in Patients With Out-of-Hospital Cardiac Arrest Who Undergo Emergency Cardiopulmonary Bypass and Percutaneous Coronary Intervention
Therapeutic hypothermia for comatose survivors of out-of-hospital cardiac arrest has demonstrated neurological benefits.
Hemofiltration During Cardiopulmonary Bypass Does Not Decrease the Incidence of Atrial Fibrillation After Cardiac Surgery
We hypothesized that hemofiltration during CPB, which may attenuate inflammation, might decrease the incidence of AF after cardiac surgery.
Preoperative Autologous Blood Donation Versus Intraoperative Blood Salvage: Intraindividual Analyses and Modeling of Efficacy in 1103 Patients
Preoperative autologous blood donation (PABD) and intraoperative blood salvage (IBS) represent established blood conservation measures. However, data comparing PABD to IBS are very sparse.
Value of Blood Transfusion in Patients With a Blood Hematocrit of 24% to 30% After Percutaneous Coronary Intervention
Bleeding is a serious complication after percutaneous coronary intervention (PCI).
The Influence of Platelet-Rich Plasma on Angiogenesis During the Early Phase of Tendon Healing
The aim of this study was to assess the effect of Platelet Rich Plasma (PRP) on angiogenesis during tendon healing.
Economics of Transfusions in Cardiac Surgery (Video)
Jim Campbell from Helena Labs discusses the economics of transfusions in cardiac surgery (27 minutes).
On-Pump versus Off-Pump Coronary-Artery Bypass Surgery
CABG without cardiopulmonary bypass (off-pump CABG) might reduce the number of complications related to the heart–lung machine.