Blood Cell Adhesion to Arterial Filters Analysis by Scanning Electron Microscopy and Real-Time PCR Assay: Observational Clinical Study in Cardiac Surgery Patients
There was adhesion of blood elements, especially nucleated platelets, on all arterial filters studied. Although the arterial filter worked as a safety device, that possibly prevented arterial embolisation, it may also have caused greater hyperfibrinolysis during cardiopulmonary bypass.
Dynamics of Appearance and Decay of Gaseous Microemboli During In Vitro Extracorporeal Circulation
We demonstrated GME formation and decay dynamics during in vitro circulation in an ECLS system with blood and glycerol. GME counts were higher in blood, likely due to varying rheological properties. There were decreases in GME levels post membrane in both groups after GME injection, with the membrane lung effectively trapping the GME, and additional reduction 10 minutes after GME injection.
Functional Brain Isolation Technique for Stroke Prevention in Thoracic Endovascular Aortic Repair
To prevent embolic stroke during thoracic endovascular aortic repair, we have adopted the brain isolation technique since June 2014 in 9 selected high-risk patients (9/134: 6.7%) having ulcerated or protruding atheromas within the proximal aorta.
Intraoperative Collection of Autologous Platelet-Rich Plasma from The Cardiopulmonary Bypass Circuit Upon Initiation of Extracorporeal Circulation
Autologous PRP can be safely collected by drawing blood from the CPB circuit, platelet count and aggregation ability significantly decreased after CPB including autologous PRP collection. Some improvement was detected in the number of the platelets count and platelet aggregation ability by administrating an autologous PRP even if autologous PRP is collected from CPB circuit.
Six-Month Survival After Extracorporeal Membrane Oxygenation for Severe COVID-19
The present findings suggested that about half of adult patients with severe COVID-19–related ARDS can be managed successfully with ECMO with sustained results at six months. Decreased arterial pH before ECMO was associated significantly with early mortality. Therefore, the authors hypothesized that initiation of ECMO therapy before severe metabolic derangements subset may improve survival rates significantly in these patients. These results should be viewed in the light of a strict patient selection policy and may not be replicated in patients with advanced age or multiple comorbidities.
VV ECMO Strategies for COVID-19, A Single Center Experience
Topics covered in this webinar included patient selection and management, cannulation preference, extracorporeal circuit design, staffing models and personal protective equipment.
Extracorporeal Membrane Oxygenation Support in Severe COVID-19
The early outcomes presented here suggest that the judicious use of ECMO support in severe COVID-19 may be clinically beneficial.
EACTA/SCA Recommendations for the Cardiac Anesthesia Management of Patients with Suspected or Confirmed COVID-19 Infection: An Expert Consensus from the European Association of Cardiothoracic Anesthesiology and Society of Cardiovascular Anesthesiologists with the endorsement from the Chinese Society of Cardiothoracic and Vascular Anesthesiology
Our document should be the basis of future Task Forces to develop a more comprehensive consensus considering new evidence uncovered during the COVID-19 pandemic.
Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles: A Clinical Feasibility Study
Bedside erythrocyte washing was clinically feasible and greatly reduced concentrations of soluble factors thought to be associated with transfusion-related adverse reactions, increasing concentrations of cell-free hemoglobin while maintaining acceptable (less than 0.8%) hemolysis.
Del Nido Cardioplegia in Coronary Artery Bypass Grafting Surgery: A Safe, Efficacious and Economic Alternative to St. Thomas Solution; An Experience from A Developing Nation
The del Nido cardioplegia was found to be efficacious, safe and more economical alternative to St. Thomas solution.
Utilization of Thromboelastogram and Inflammatory Markers in the Management of Hypercoagulable State in Patients with COVID-19 Requiring ECMO Support
The results of this case report show successful management of a hypercoagulable state among COVID-19 patients requiring ECMO support by utilization of inflammatory markers and TEG.
Clinical and Technical Limitations of Cerebral and Somatic Near-Infrared Spectroscopy as an Oxygenation Monitor
This narrative review explores those clinical and technical limitations and proposes solutions and alternatives in order to avoid some of those pitfalls.