Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review
A comprehensive understanding of TTS pathophysiology and evidence-based treatments are lacking, and specific and effective treatments are urgently required. This paper reviews the pathophysiology of this fascinating syndrome; what is known from both clinical and preclinical studies, including review of the evidence for microvascular dysfunction, myocardial beta-adrenergic signaling, inflammation, and electrophysiology; and where focused research needs to fill gaps in understanding TTS.
Enhanced Hemocompatibility and In Vivo Analytical Accuracy of Intravascular Potentiometric Carbon Dioxide Sensors via Nitric Oxide Release
The accurate, continuous monitoring of blood PCO2 levels achieved with this new IV NO releasing PCO2 sensor configuration could help better manage hospitalized patients in critical care units.
Analysis of Risk Factors for In-Hospital Mortality In 177 Patients Who Underwent Isolated Coronary Bypass Grafting and Received Intra Aortic Balloon Pump
Our analysis showed that increased preoperative plasma creatinine, postoperative renal dysfunction, and CPB time negatively affected the outcomes of patients who received intraoperative IABP insertion.
A Descriptive Study of Perioperative Hemodynamics in Open Cardiac Surgery Patients
This is a large registry based study describing the perioperative hemodynamic profile of patients undergoing cardiac surgery and the results enhance our understanding of age-differentiated values of CI and SvO2 in this specific population.
GTH 2021 State of the Art—Cardiac Surgery: The Perioperative Management of Heparin-Induced Thrombocytopenia in Cardiac Surgery
The management of HIT can be highly challenging, and requires a multidisciplinary approach. In this short review, the different perioperative strategies to run cardiopulmonary bypass will be summarized.
Total Circulatory Arrest as A Support Modality in Congenital Heart Surgery: Review and Current Evidence
This review analyzes the history, physiology, techniques of DHCA, as well as other alternative strategies like selective cerebral perfusion and presents the current available evidence.
Avoiding Use of Total Circulatory Arrest in The Practice of Congenital Heart Surgery
In this review we have discussed the various physiological and technical factors involved in conduct of SACP in paediatric cardiac surgery and outcomes with SACP.
Platelet, Red Cell, and Endothelial Activation and Injury During Extracorporeal Membrane Oxygenation
ECMO is associated with a highly variable, sustained increase in platelet, red-cell, and endothelial activation and injury that is a combination of circuit and transfusion related events, the patients underlying condition and possibly genetic influences on blood cell activation and injury. Extracellular vesicle measurements may improve our understanding of cellular activation and injury during ECMO as we work to improve the biocompatibility of these systems.
Recirculation in Extracorporeal Membrane Oxygenation: The Warning Comes From the Cannula
In conclusion, poor oxygenation under ECMO with alternation of bright red and dark red blood in the drainage cannula must refer to recirculation by cannula misplacement. Transesophageal echocardiography must be performed first when there is a lack of oxygenation during venovenous ECMO.
Preoperative Neutrophil and Lymphocyte Ratio as a Predictor of Mortality and Morbidity After Cardiac Surgery
The interpretation and utilisation of readily available haematological markers can provide further risk stratification data to the surgeon when considering the postoperative cardiac surgery risks.
The “TIDE”-Algorithm for the Weaning of Patients With Cardiogenic Shock and Temporarily Mechanical Left Ventricular Support With Impella Devices
Mechanical circulatory support (MCS) is often required to stabilize therapy-refractory cardiogenic shock patients. We here propose a novel cardiovascular physiology-based weaning algorithm for MVS.
Prone Positioning during Venovenous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Multicenter Cohort Study and Propensity-matched Analysis
The aim of the study was to assess the feasibility, safety, and effect on oxygenation and lung mechanics of PP during ECMO. As a secondary exploratory aim, we assessed the association between PP and hospital mortality.