Acute Response of Human Aortic Endothelial Cells to Loss of Pulsatility as Seen during Cardiopulmonary Bypass
These results suggest that even short-term exposure to continuous flow can potentially activate pro-inflammatory/pro-angiogenic signaling in cultured HAECs and pulsatile flow may be a successful strategy in reducing the undesirable sequalae following continuous flow CPB.
The Diagnostic Accuracy of Procalcitonin In Infectious Patients After Cardiac Surgery: A Systematic Review and Meta-Analysis
This study indicated that PCT is a promising marker for the diagnosis of sepsis for those patients who undergo cardiac surgery.
Can Peroperative Neutrophil To Lymphocyte Ratio Change (Deltanlr) Be Used as a Parameter in Predicting Acute Renal Failure Following Coronary Bypass Operations With Cardiopulmonary Bypass?
In this study, we have shown that peroperative NLR changes can be used as an effective parameter to predict ARF developing following CABG operations.
A Computational Fluid Dynamics Study of the Extracorporeal Membrane Oxygenation-Failing Heart Circulation
Using an idealized geometry of the aorta and its major branches and a peripherally inserted return cannula terminating in the iliac artery, computational fluid dynamic simulations were performed to (1) quantify perfusion as function of relative ECMO flow and (2) describe the watershed region produced by the collision of antegrade flow from the heart and retrograde ECMO flow.
Dual Veno-Arterial Extra-Corporeal Membrane Oxygenation Support in A Patient with Refractory Hyperdynamic Septic Shock: A Case Report
The commencement of a second jugulo-axillary VA ECMO secured a total blood flow of 14.3 L/min, which restored perfusion pressure and successfully bridged patient over the period of critical haemodynamic instability and ultimately may have facilitated recovery.
Synchronous Liver Resection, Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Colorectal Liver and Peritoneal Metastases: A Systematic Review and Meta-analysis
Synchronous liver resection, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal liver and peritoneal metastases has traditionally been contraindicated. More recent clinical practice has begun to promote this aggressive treatment in select patients.
My Thoughts: Unspoken Truths About Gender Inequality in Surgery Across Different Cultures and Income Levels
Keywords Sexism Gender Surgeons Internship Residency
Systematic Reviews and Meta-Analyses in Cardiac Surgery: Rules of the Road – Part 1
The aim of the first part of this expert review is to discuss the limits and pitfalls of the meta-analytic approach and provide guidance on how to perform trial-level meta-analyses, with particular reference to the identification of an appropriate research question, the definition and registration of the protocol, the search strategy, the study selection, and the data abstraction.
Systematic Reviews and Meta-Analyses in Cardiac Surgery: Rules of the Road – Part 2
The aim of the second part of this expert review is to provide guidance on how to appropriately perform trial level meta-analyses, with particular focus on the quality assessment of the included studies, the choice of the appropriate statistical approach, the methods to deal with heterogeneity (including subgroup, meta-regression, and sensitivity analyses), and the appraisal of publication bias.
Cardiopulmonary Bypass Suppresses Forkhead Box O3 and Downstream Autophagy in the Diabetic Human Heart
Compared with nondiabetic patients, there was no significant upregulation of FOXO3α in diabetic patients, which could possibly explain the lack of upregulation of the autophagy process after CPB. FOXO3α could potentially serve as a therapeutic target to improve cellular homeostasis.
Peer-Review Of “A History of Cardiac Surgery: An Adventurous Voyage from Antiquity to The Artificial Heart”
The novelty of the book resides it has been written by a cardiac surgeon himself and not by a professional historian. It covers the voyage from extra cardiac operations to “closed” and “open” heart surgery with extracorporeal circulation. The book is strongly recommend to Cardiovascular Pathologists since our discipline was born with the contemporary cardiac surgery.
Collateral Flow at Circle of Willis In Healthy Condition
This research tries to construct new platform in cerebral circulation analyzing method by reliable experimental in-vitro approach. The outcomes of this study demonstrate that communicating arteries especially anterior communicating artery (ACoA) is main artery in CAC flow distribution.