Optimal Intraoperative Anticoagulation Strategy in Patients Undergoing Off-Pump Coronary Artery Bypass
The question addressed was what the optimal intraoperative anticoagulation strategy should be in patients undergoing off-pump coronary artery bypass graft (CABG) surgery
Long-term Mechanical Circulatory Support (Destination Therapy): On Track to Compete with Heart Transplantation?
Average 2-year survival after cardiac transplantation is approximately 80%.
Change in Heparin Potency and Effects on the Activated Clotting Time in Children Undergoing Cardiopulmonary Bypass
In this investigation we provide objective evidence that the level of anticoagulation after the initial pre-CPB heparin bolus as assessed by the ACT is significantly less with use of the new heparin.
Mechanical Circulatory Support for Cardiogenic Shock
In this review, we discuss the role of each of these circulatory support devices in the management of acute cardiac failure.
Cerebral and Lower Limb Near-Infrared Spectroscopy in Adults on Extracorporeal Membrane Oxygenation
Percutaneous femoral venoarterial (VA) or jugular venovenous (VV) extracorporeal membrane oxygenation (ECMO) can result in delivery of hypoxic blood to the brain, coronaries, and upper extremities
The Effect of Cardiopulmonary Bypass Prime Volume on the Need for Blood Transfusion after Pediatric Cardiac Surgery
There is increasing awareness that erythrocyte transfusions after pediatric cardiac surgery have deleterious effects.
Changes in Mechanical Fragility and Free Hemoglobin Levels after Processing Salvaged Cardiopulmonary Bypass Circuit Blood with a Modified Ultrafiltration Device
This study evaluated the extent of hemolysis, the mechanical fragility index (MFI), and the amount of plasma free hemoglobin (PFHb) created after processing with the MUF device.
Washing of Banked Blood by Three Different Blood Salvage Devices
Washing improves the quality of stored RBCs, and autotransfusion devices have been proposed for intraoperative processing, but these devices were designed for diluted wound blood, and limited data on their performance with RBCs are available.
Device Thrombogenicity Emulation: A Novel Method for Optimizing Mechanical Circulatory Support Device Thromboresistance
To address the unmet need for enhancing the thromboresistance of these devices to extend their long term use, we developed a universal predictive methodology entitled Device Thrombogenicity Emulation (DTE) that facilitates optimizing the thrombogenic performance of any MCS device--ideally to a level that may obviate the need for mandatory anticoagulation.
Current Status of Mechanical Circulatory Support: a Systematic Review
This paper outlines the current status of mechanical circulatory support.
Evaluation of Appropriate Serologic Testing for Suspected Heparin-Induced Thrombocytopenia
Purpose The predictive value of clinical "4-T's" scoring in patient selection for serologic testing to confirm suspected heparin-induced thrombocytopenia (HIT) was evaluated.
Characterizing the Impact of Minor Cannula Design Modification
The aim of this study was to investigate the effect of the internal diameter of the extracorporeal connecting tube of venous cannulas on flow rate (Q), pressure drop (delta P), and cannula resistance (delta P/Q²) values, using a computer assisted test bench.