The Efficacy of Parecoxib on Systemic Inflammatory Response Associated with Cardiopulmonary Bypass During Cardiac Surgery
Intraoperative parecoxib attenuated systemic inflammatory response associated with CPB during cardiac surgery and lowered the biochemical markers of myocardial injury.
Cerebral and Somatic Near-Infrared Spectroscopy Measurements During Fluid Challenge in Cardiac Surgery Patients: A Descriptive Pilot Study
Little is known about changes in near-infrared spectroscopy (NIRS)-derived cerebral (rSO(2)b) and somatic (rSO(2)s) oxygen saturation during a fluid challenge.
Fibrinogen Function is Impaired in Whole Blood from Patients with Cyanotic Congenital Heart Disease
Patients with CCHD are hypocoagulable mainly due to impaired fibrinogen function.
The Influence of Heparin Resistance on Postoperative Complications in Patients Undergoing Coronary Surgery
Severe form of heparin resistance (expressed by the ACT less than 480 seconds after 400 U/kg heparin) was an independent predictor of death.
The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design
The "Age of Blood Evaluation" (ABLE) study (ISRCTN44878718) is a double-blind, multicenter, parallel randomized controlled clinical trial.
Longer Blood Storage is Associated with Suboptimal Outcomes in High-Risk Pediatric Cardiac Surgery
The freshest RBC units available should be used for pediatric cardiac operations expected to require more than 4 units or more than 150 mL/kg of allogeneic RBC transfusions, with no units more than 14 days old being transfused whenever possible.
Effects of Pre-Storage Leukoreduction on Stored Red Blood Cells Signaling: A Time-Course Evaluation from Shape to Proteome
The introduction of pre-storage leukoreduction in the preparation of standard RBCs intended for transfusion provided significant improvement in the quality of labile products and their post transfusion viability and effects, although the literature data are controversial.
Transfusion Immunomodulation – The Case for Leukoreduced and (Perhaps) Washed Transfusions
The present review will focus on two approaches, leukoreduction and saline washing, as means to reduce adverse transfusion outcomes.
Transfusion Thresholds and other Strategies for Guiding Allogeneic Red Blood Cell Transfusion
The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers).
Fenoldopam and Acute Renal Failure in Cardiac Surgery: A Meta-Analysis of Randomized Placebo-Controlled Trials
This analysis suggests that fenoldopam reduces acute kidney injury in patients undergoing cardiac surgery.
ABO Incompatible Platelets: Risks versus Benefit
This review summarizes recent developments in the area of ABO compatibility and platelet transfusion and examines the risks and benefits associated with transfusion practices allowing for platelet ABO incompatibility.
Increased Long-Term Mortality with Plasma Transfusion after Coronary Artery Bypass Surgery
This study explores the relation between the transfusion of different blood components and long-term mortality.