Blood Substitutes: Evolution from Non Carrying to Oxygen-and Gas-Carrying Fluids
The development of oxygen (O2)-carrying blood substitutes has evolved from the goal of replicating blood O2 transport properties to that of preserving microvascular and organ function, reducing the inherent or potential toxicity of the material used to carry O2, and treating pathologies initiated by anemia and hypoxia.
Cardiovascular Tissue Engineering Research Support at the National Heart, Lung, and Blood Institute
This article is a review of the tissue engineering programs of the National Heart, Lung, and Blood Institute, which support research efforts to translate novel approaches for the treatment of cardiovascular disease.
Fabrication of Small-Diameter Vascular Scaffolds by Heparin-Bonded P(LLA-CL) Composite Nanofibers to Improve Graft Patency
The poor patency rate following small-diameter vascular grafting remains a major hurdle for the widespread clinical application of artificial bloodvessels to date.