Comparative Cost-Effectiveness of the HeartWare Versus HeartMate II Left Ventricular Assist Devices Used in the United Kingdom National Health Service Bridge-To-Transplant Program for Patients with Heart Failure
The United Kingdom National Health Service (UK NHS) has financed a BTT program in which the predominant LVADs used have been the HeartMate II (HM II; Thoratec, Pleasanton, CA) and HeartWare (HW; HeartWare International, Inc. Framingham, MA). We aimed to compare the cost-effectiveness of the use of these within the NHS program.
Assessment of Myocardial Viability and Left Ventricular Function in Patients Supported by a Left Ventricular Assist Device
We aimed to develop a non-invasive imaging protocol to serially quantify native cardiac structure, function, and myocardial viability while at reduced LVAD support.
Mechanical Cardiac Support in Children with Congenital Heart Disease with Intention to Bridge to Heart Transplantation
A significant number of children affected by congenital heart disease (CHD) develop heart failure early or late after surgery, and heart transplantation (OHTx) remains the last treatment option. Due to shortage of donor organs in paediatric group, mechanical circulatory support (MCS) is now routinely applied as bridging strategy to increase survival on the waiting list for OTHx. We sought to assess the impact of MCS as intention to bridge to OHTx in patients with CHD less than 16 years of age.
The Practical Role of Echocardiography in Selection, Implantation, and Management of Patients Requiring LVAD Therapy
An integrated approach using basic echocardiography is critical to patient selection, implantation, and continued surveillance and success of patients with left ventricular assist devices.
Impact of Different Creatinine Measurement Methods on Liver Transplant Allocation
The model for end-stage liver disease (MELD) score is used in many countries to prioritize organ allocation for the majority of patients who require orthotopic liver transplantation. This score is calculated based on the following laboratory parameters: creatinine, bilirubin and the international normalized ratio (INR).
Balloon Aortic Valvuloplasty (BAV) as a Bridge to Aortic Valve Replacement in Cancer Patients Who Require Urgent Non-Cardiac Surgery
Balloon aortic valvuloplasty (BAV) is a percutaneous treatment option for severe, symptomatic aortic stenosis. Due to early restenosis and failure to improve long term survival, BAV is considered a palliative measure in patients who are not suitable for open heart surgerydue to increased perioperative risk.
The Association Between Tranexamic Acid and Convulsive Seizures after Cardiac Surgery: A Multivariate Analysis in 11 529 Patients
Convulsive seizures are a serious postoperative complication after cardiac surgery. As tranexamic acid is the only modifiable factor, its administration, particularly in doses exceeding 80 mg.kg(-1), should be weighed against the risk of postoperative seizures.
Intraoperative Cardiac Arrest and Mortality in Trauma Patients. A 14-yr Survey from a Brazilian Tertiary Teaching Hospital
Little information on the factors influencing intraoperative cardiac arrest and its outcomes in trauma patients is available. This survey evaluated the associated factors and outcomes of intraoperative cardiac arrest in trauma patients in a Brazilian teaching hospital between 1996 and 2009.
Profound Hypothermia Compared with Moderate Hypothermia in Repair of Acute Type A Aortic Dissection
To determine the impact of the degree of hypothermia on surgical outcomes in patients undergoing repair of acute type A aortic dissection.
Development of a Hemodynamically Optimized Outflow Cannula for Cardiopulmonary Bypass
These results suggest that the MMC outperforms standard CPB cannulas.
Weight-Based versus Set Dosing of Vancomycin for Coronary Artery Bypass Grafting or Aortic Valve Surgery
Weight-based vancomycin dosing before coronary artery bypass grafting or valve replacement results in vancomycin concentrations greater than 15 μg/mL consistently more than does standard 1-g dosing.
Long-term Outcomes of Coronary Artery Bypass Grafting Patients Supported Preoperatively with an Intra-Aortic Balloon Pump
In patients supported preoperatively with an IABP, better early and long-term results were strongly related to younger age,