Platelet Function During Cardiopulmonary Bypass Using Multiple Electrode Aggregometry: Comparison of Centrifugal and Roller Pumps
Blood trauma may be lower with centrifugal pumps (CPs) than with roller pumps (RPs) during cardiopulmonary bypass (CPB), because, unlike RPs, CPs do not compress the tubing, and shear stress is considered lower in CPs than in RPs. However, relative platelet function remains unclear. Using multiple electrode aggregometry (MEA), we compared platelet function with CP and RP.
Pathophysiology of Cardiopulmonary Bypass: Current Strategies for the Prevention and Treatment of Anemia, Coagulopathy, and Organ Dysfunction
In this review, pathophysiological aspects of CPB are considered from a practical point of view, and preventive strategies for hemodilutional anemia, coagulopathy, inflammation, metabolic derangement, and neurocognitive and renal dysfunction are discussed.
Protamine Requirements in Cardiac Surgery: Effect of Changes in the Heparin Reference Standard
UFH (unfractionated heparin) and protamine are integral to cardiac surgery, and inappropriate dosing can predispose to coagulopathy and hemorrhage.
Evidence-Based Use of FFP: the Influence of a Priming Strategy Without FFP During CPB on Postoperative Coagulation and Recovery in Pediatric Patients
Our present study observed the effects of a priming strategy without fresh frozen plasma (FFP) during cardiopulmonary bypass (CPB) on postoperative coagulation and clinical recovery in pediatric patients, aiming to supply new evidence for evidence-based use of FFP.
The Impact of Hydroxyethyl Starches in Cardiac Surgery: A Meta-Analysis
Recent studies in septic patients showed that adverse effects of hydroxyethyl starches (HES) possibly outweigh their benefits