Brain and Muscle Oxygen Saturation Combined with Kidney Injury Biomarkers Predict Cardiac Surgery Related Acute Kidney Injury
Brain and muscle oxygen saturation 20 min after CPB could be considered early parameters possibly related to CS-AKI risk, especially in patients with increased cystatin C and NGAL levels.
Thrombocytosis and Neutrophilia Associated with Oxygenator Failure and Protamine Reaction after Cardiopulmonary Bypass: A Case Report and Literature Review
The patient subsequently suffered a severe protamine reaction that was successfully managed. A review of the literature of similar patients and the relevant cellular and biochemical mechanisms in this setting are presented, with potential therapeutic approaches to prevent such complications noted.
Impact of Cardiopulmonary Bypass on Neurogenesis and Cortical Maturation
Our results provide novel insights into cellular mechanisms contributing to CHD-induced neurological impairments. Further refinement of CPB hardware and techniques is necessary to improve long-term frontal cortical dysmaturation observed in children with CHD.
Clinical Monitoring of Activated Clotting Time during Cardiothoracic Surgery: Comparing the Hemochron® Response and Hemochron® Signature Elite
The Elite was more reliable, but the variation was higher for the Elite than the Response. The observed positive bias in the Response compared to the Elite could affect heparin administration during surgery making the two systems not interchangeable.
The Importance of Autologous Blood Transfusion in Lung Transplantation and Cardiovascular Surgeries
Autologous blood transfusion may prevent the development of transfusion-related complications by reducing the amount of allogenic transfusion in major surgical procedures. In our study, the autologous blood transfusion was used in critical patients with major bleeding and, therefore, the total amount of transfused blood/blood product was higher in these patients. Nevertheless, lower complication rates in this patient group emphasize the importance of autologous blood transfusion.
Implementation of an Electronic Identification System in the Setting of Perioperative Autologous Cell Salvage Transfusion: Experience at A University Hospital.
Our observations suggest that a bar code-based EIS can be successfully applied to PACS transfusion, as well as allogeneic blood transfusion in operating rooms.
Reduced Systemic Nitric Oxide Bioavailability Parallels Microvascular Endothelial Dysfunction during Cardiopulmonary Bypass
The impairment of microvascular endothelial function during CPB in cardiac surgery for the correction of congenital heart defects appears to be related to a reduced systemic bioavailability of NO, resulting from the inflammatory and pro-oxidative response typical of this surgical procedure.
Early Biochemical Markers in the Assessment of Acute Kidney Injury in Children after Cardiac Surgery
We showed that plasma CysC and urinary NGAL could reliably predict the development of acute kidney injury. Measurement of early biochemical markers in plasma and urine, individually and combination, may predict the development of cardiac surgery-associated acute kidney injury in children.
Early Outcomes of Cardiac Surgical Patients Who Developed COVID-19 in the Peri-Operative Period-Results from An Online Survey
The development of peri-operative COVID in cardiac surgery was associated with very high mortality. We believe that it is time for us as a fraternity to introspect and adapt to the changing practice environment, furthered by research and revision of guidelines.
Effects of Rewarming with Extracorporeal Membrane Oxygenation to Restore Oxygen Transport and Organ Blood Flow after Hypothermic Cardiac Arrest in A Porcine Model
Thus, like continuous CPR, ECMO rewarming plays a crucial role in “the chain of survival” when resuscitating victims of hypothermic cardiac arrest.
Education in Evidence-Based Health Care: Never A Greater Need
The pandemic has highlighted the importance of health science and research that is efficiently produced, evaluated and acted on. Hand in hand with this comes the ability to ask, find, appraise and apply evidence to support effective decisions. These abilities are essential skills—skills that need to be taught. Where there is a need to be taught, there is a need for people to teach. The final article in the series aims to aid EBHC educators in this mission. Through collaboration and consensus, our peers come together to provide aspiring EBHC teachers a resource of their go-to articles in support of effective and inspirational teaching and education.
Extracorporeal Membrane Oxygenation in Jehovah’s Witness Patients: Case Report, Literature Review, and Summary of Recommendations
We describe the use of a bloodless approach to reduce the waste of blood, avoiding anticoagulation, and improving red blood cell production. We then summarize the current literature on the use of ECMO in Jehovah’s Witness patients and, fi